CAS 100648-13-3
:Triclabendazole sulfoxide
Description:
Triclabendazole sulfoxide is a chemical compound derived from triclabendazole, which is primarily used as an anthelmintic agent in veterinary medicine, particularly for the treatment of liver fluke infections in livestock. The sulfoxide form is characterized by the presence of a sulfur atom bonded to an oxygen atom, which contributes to its pharmacological properties. This compound exhibits a high degree of lipophilicity, allowing it to effectively penetrate biological membranes and exert its therapeutic effects. Triclabendazole sulfoxide is known for its selective action against certain parasitic worms, making it valuable in managing parasitic infections. Its mechanism of action involves disrupting the energy metabolism of the parasites, leading to their eventual death. Additionally, it has a relatively low toxicity profile in target animals, which enhances its safety for veterinary use. The compound is typically administered orally and is subject to regulatory scrutiny to ensure its safe use in food-producing animals. Overall, triclabendazole sulfoxide plays a significant role in veterinary parasitology.
Formula:C14H9Cl3N2O2S
InChI:InChI=1/C14H9Cl3N2O2S/c1-22(20)14-18-9-5-8(16)12(6-10(9)19-14)21-11-4-2-3-7(15)13(11)17/h2-6H,1H3,(H,18,19)
SMILES:CS(=O)c1[nH]c2cc(c(cc2n1)Oc1cccc(c1Cl)Cl)Cl
Synonyms:- 6-Chloro-5-(2,3-Dichlorophenoxy)-2-(Methylsulfinyl)-1H-Benzimidazole
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Found 14 products.
Triclabendazole Related Compound A (5-Chloro-6-(2,3-dichlorophenoxy)-2-(methylsulfinyl)-1H-benzimidazole)
CAS:Heterocyclic compounds with nitrogen hetero-atom(s) only, aromatic or modified aromatic, nesoiFormula:C14H9Cl3N2O2SColor and Shape:Off-White Crystalline PowderMolecular weight:373.945031H-Benzimidazole, 6-chloro-5-(2,3-dichlorophenoxy)-2-(methylsulfinyl)-
CAS:Formula:C14H9Cl3N2O2SPurity:97%Color and Shape:SolidMolecular weight:375.65756-Chloro-5-(2,3-Dichlorophenoxy)-2-(Methylsulfinyl)-1H-Benzo[D]Imidazole
CAS:6-Chloro-5-(2,3-Dichlorophenoxy)-2-(Methylsulfinyl)-1H-Benzo[D]ImidazolePurity:97%Molecular weight:375.66g/molTriclabendazole EP Impurity A-13C-d3 (Triclabendazole S-Oxide-13C-d3)
CAS:Formula:C1313CH6D3Cl3N2O2SColor and Shape:White To Off-White SolidMolecular weight:379.66Triclabendazole EP Impurity A (Triclabendazole S-Oxide)
CAS:Formula:C14H9Cl3N2O2SColor and Shape:Off-White SolidMolecular weight:375.65Triclabendazole-sulfoxide
CAS:Controlled ProductFormula:C14H9Cl3N2O2SColor and Shape:NeatMolecular weight:375.665-Chloro-6-(2,3-dichlorophenoxy)-2-(methylsulfinyl)-1H-benzimidazole (Triclabendazole Sulfoxide)
CAS:Color and Shape:NeatTriclabendazole sulfoxide
CAS:<p>TCBZ-SO, a Triclabendazole metabolite, blocks ABCG2/BCRP and has anti-parasitic properties.</p>Formula:C14H9Cl3N2O2SPurity:98.02%Color and Shape:SolidMolecular weight:375.66Triclabendazole Sulfoxide
CAS:<p>Applications Triclabendazole Sulfoxide is a metabolite of Triclabendazole (T774175), the only anthelmintic drug, which is active against immature, mature and adult stages of fluke.<br>References Whelan, M., et al.: J. Chromato., 1275, 41 (2013); Barrera, S., et al.; Antimicrob. Agent. Chemother., 56, 3535 (2012);<br></p>Formula:C14H9Cl3N2O2SColor and Shape:ColourlessMolecular weight:375.66Triclabendazole Sulfoxide-D3
CAS:Controlled Product<p>Applications Triclabendazole Sulfoxide-D3 is a stable isotopically labelled metabolite of Triclabendazole (T774175), an anthelmintic.<br>References Wolff, K., et al.: Vet. Parasitol., 13, 145 (1983)<br></p>Formula:C14H6D3Cl3N2O2SColor and Shape:NeatMolecular weight:378.68Triclabendazole sulfoxide
CAS:<p>Triclabendazolesulfoxide is a benzimidazole compound that binds to the ATP-binding cassette transporter, which is a protein in the liver that transports various drugs and other molecules. It is used to treat infections caused by roundworms, hookworms, and pinworms. Triclabendazolesulfoxide has been shown to have pharmacokinetic properties similar to triclabendazole, but with decreased protein binding. Triclabendazolesulfoxide has been shown to be an effective anthelmintic drug against roundworm infections in mice.</p>Formula:C14H9Cl3N2O2SPurity:Min. 95%Color and Shape:PowderMolecular weight:375.66 g/molTriclabendazole-sulfoxide 100 µg/mL in Acetonitrile
CAS:Formula:C14H9Cl3N2O2SColor and Shape:Single SolutionMolecular weight:375.66










