CAS 1006718-20-2

Terazosin (piperazine D8)

Description:

Terazosin, also known as piperazine D8, is an alpha-1 adrenergic antagonist primarily used in the treatment of hypertension and benign prostatic hyperplasia (BPH). It works by relaxing blood vessels and smooth muscle in the prostate and bladder neck, facilitating easier urination and lowering blood pressure. The chemical structure of terazosin includes a piperazine ring, which contributes to its pharmacological activity. It is typically administered orally and has a relatively long half-life, allowing for once-daily dosing. Terazosin is well-absorbed in the gastrointestinal tract, with peak plasma concentrations occurring within a few hours after ingestion. Common side effects may include dizziness, fatigue, and orthostatic hypotension, particularly after the first dose. Due to its mechanism of action, terazosin can also lead to improvements in urinary flow and reduction in symptoms associated with BPH. As with any medication, it is essential to use terazosin under medical supervision to monitor for potential interactions and side effects.

Formula: C₁₉H₂₅N₅O₄

Synonyms:

• Terazosin (piperazine D8)
• Terazosin-d8

Terazosin-d8

CAS: 1006718-20-2

Formula: C₁₉H₁₇D₈N₅O₄

Color and Shape: White To Off-White Solid

Molecular weight: 395.49

Ref: 4Z-T-7517

Terazosin (piperazine D8)

Controlled Product

CAS: 1006718-20-2

Applications Terazosin (piperazine D8) is labelled Terazosin (T105000, HCl salt; T105005, HCl Dihydrate) which is an α-1-adrenergic blocker related to prazosin.
References Patterson, S.E., et al.: J. Chromatog., 311, 206 (1984); Fort, F.L., et al.: Drug Chem. Toxicol., 7, 435 (1984); Lepor, H., et al.: J. Urol., 148, 1467 (1992)

Formula: C₁₉H₁₇D₈N₅O₄

Color and Shape: Neat

Molecular weight: 395.48

Ref: TR-T105002