CAS 10075-24-8

Imipramine pamoate

Description:

Imipramine pamoate is a pharmaceutical compound primarily used as an antidepressant, classified under the tricyclic antidepressants (TCAs). It is a salt form of imipramine, which is known for its efficacy in treating major depressive disorders and certain anxiety disorders. The pamoate salt enhances the drug's solubility and bioavailability. Imipramine pamoate exhibits a complex mechanism of action, primarily functioning as a norepinephrine and serotonin reuptake inhibitor, which increases the levels of these neurotransmitters in the synaptic cleft, thereby improving mood and emotional stability. The compound is typically administered via intramuscular injection, allowing for prolonged release and sustained therapeutic effects. Its pharmacokinetics involve extensive metabolism in the liver, with a variety of metabolites contributing to its overall therapeutic profile. Common side effects may include sedation, dry mouth, and weight gain, among others. Due to its potential for side effects and interactions, careful monitoring is essential during treatment. Overall, imipramine pamoate represents an important option in the pharmacological management of depression and related disorders.

Formula: C₂₃H₁₆O₆·2C₁₉H₂₄N₂

InChI: InChI=1S/C23H16O6.C19H24N2/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21/h1-10,24-25H,11H2,(H,26,27)(H,28,29);3-6,8-11H,7,12-15H2,1-2H3

InChI key: InChIKey=SBDXQUVAAJKLDH-UHFFFAOYSA-N

SMILES: C(C=1C2=C(C=C(C(O)=O)C1O)C=CC=C2)C=3C4=C(C=C(C(O)=O)C3O)C=CC=C4.C(CCN(C)C)N1C=2C(CCC=3C1=CC=CC3)=CC=CC2

Synonyms:

• 2-Naphthalenecarboxylic acid, 4,4′-methylenebis[3-hydroxy-, compd. with 10,11-dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine (1:2)
• 2-Naphthoic acid, 4,4′-methylenebis[3-hydroxy-, compd. with 5-[3-(dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine
• 2-Naphthoic acid, 4,4′-methylenebis[3-hydroxy-, compd. with 5-[3-(dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine (1:2)
• 4,4'-methanediylbis(3-hydroxynaphthalene-2-carboxylic acid) - 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine (1:2)
• 5H-Dibenz[b,f]azepine, 5-[3-(dimethylamino)propyl]-10,11-dihydro-, 4,4′-methylenebis[3-hydroxy-2-naphthoate] (2:1)
• 5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N,N-dimethyl-, 4,4′-methylenebis[3-hydroxy-2-naphthalenecarboxylate] (2:1)
• Imipramine Pamoate

Imipramine Pamoate

CAS: 10075-24-8

Antidepressants, tranquilizers and other psychotherapeutic agents, nesoi

Formula: C₂₃H₁₆O₆·2C₁₉H₂₄N₂

Color and Shape: Yellow Powder

Molecular weight: 388.09469

Ref: 45-1338481

Imipramine Pamoate

CAS: 10075-24-8

Formula: C₄₀H₅₀N₂·C₂₃H₁₆O₆

Color and Shape: Pale Yellow Solid

Molecular weight: 558.86 388.38

Ref: 4Z-I-018

Imipramine Pamoate

Controlled Product

CAS: 10075-24-8

Applications Imipramine Pamoate is a tricyclic antidepressant.
References Ramesha, Andagar R., et al.: U.S. Pat. Appl. Publ., US 20150225349 A1 20150813 (2015)

Formula: C₆₁H₆₄N₄O₆

Color and Shape: Neat

Molecular weight: 949.18

Ref: TR-I466008

Imipramine pamoate

Controlled Product

CAS: 10075-24-8

Imipramine pamoate is a kinase inhibitor that has been shown to induce apoptosis in human cancer cells. It is an analog of amphetamine and has potent anticancer activity. Imipramine pamoate works by inhibiting the activity of several kinases, including protein kinase C and mitogen-activated protein kinase (MAPK), which are involved in cell growth and survival. This drug has been found to be effective against a variety of tumors, including breast, lung, and colon cancers. Imipramine pamoate is excreted in urine and can be used as a biomarker for cancer diagnosis or monitoring.

Formula: C₆₁H₆₄N₄O₆

Purity: Min. 95%

Molecular weight: 949.2 g/mol

Ref: 3D-KAA07524

Imipramine pamoate

CAS: 10075-24-8

Imipramine pamoate, a potent antidepressant [1] [2], is a chemical compound widely recognized for its efficacy in treating depressive disorders.

Formula: C₆₁H₆₄N₄O₆

Color and Shape: Solid

Molecular weight: 949.18

Ref: TM-T82075