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CAS 10078-27-0

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Prochlorperazine Sulfoxide

Description:
Prochlorperazine sulfoxide is a chemical compound derived from prochlorperazine, which is primarily used as an antipsychotic and antiemetic medication. It is characterized by its sulfoxide functional group, which contributes to its pharmacological properties. The compound typically appears as a white to off-white crystalline solid and is soluble in organic solvents but has limited solubility in water. Prochlorperazine sulfoxide is known for its role in the treatment of severe nausea and vomiting, particularly in patients undergoing chemotherapy or surgery. Its mechanism of action involves antagonism of dopamine receptors in the central nervous system, which helps to alleviate symptoms. Additionally, the sulfoxide form may exhibit different pharmacokinetic and pharmacodynamic profiles compared to its parent compound, potentially influencing its therapeutic efficacy and side effects. As with many pharmaceuticals, safety and efficacy are paramount, and it is essential to consider potential interactions with other medications and individual patient factors when using this compound in clinical settings.
Formula:C20H24ClN3OS
InChI:InChI=1/C20H24ClN3OS/c1-22-11-13-23(14-12-22)9-4-10-24-17-5-2-3-6-19(17)26(25)20-8-7-16(21)15-18(20)24/h2-3,5-8,15H,4,9-14H2,1H3
SMILES:CN1CCN(CCCN2c3ccccc3S(=O)c3ccc(cc23)Cl)CC1
Synonyms:
  • 2-Chloro-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine 5-Oxide
  • 2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine 5-oxide
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