CAS 100898-63-3: 5'-O-(4,4'-Dimethoxytrityl)-N4-acetyl-2'-deoxycytidine

Description: 5'-O-(4,4'-Dimethoxytrityl)-N4-acetyl-2'-deoxycytidine, with the CAS number 100898-63-3, is a modified nucleoside that plays a significant role in the field of molecular biology and biochemistry, particularly in the synthesis of oligonucleotides. This compound features a deoxycytidine base, which is a building block of DNA, modified at the 5' position with a dimethoxytrityl (DMT) protecting group. The DMT group is commonly used to protect the hydroxyl group during the synthesis of nucleotides, allowing for selective reactions. Additionally, the N4-acetyl modification enhances the stability and solubility of the nucleoside. This compound is typically utilized in solid-phase synthesis techniques for oligonucleotide production, where its protective groups can be selectively removed to facilitate the sequential addition of nucleotides. Its structural characteristics contribute to its utility in research and therapeutic applications, including gene therapy and the development of antisense oligonucleotides. Overall, this compound exemplifies the intricate modifications that enhance the functionality of nucleosides in biochemical applications.

Formula: C₃₂H₃₃N₃O₇

Synonyms:

• N4-Acetyl-2'-deoxy-5'-O-DMT-D-cytidine
• N4-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine
• 5'-O-(4,4'-Dimethoxytrityl)-N4-acetyl-2'-deoxycytidine (synthetic)
• Dmt-Ac-dC
• 5'-DMTr-N4-acetyl-2'-deoxycytidine

Cytidine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-

CAS: 100898-63-3

• Formula: C₃₂H₃₃N₃O₇
• Purity: 97%
• Color and Shape: Solid
• Molecular weight: 571.6203

N4-Acetyl-2?-Deoxy-5?-O-Dmt-Cytidine

CAS: 100898-63-3

• Purity: 98%
• Molecular weight: 571.62g/mol

N4-Acetyl-2''-deoxy-5''-O-DMT-cytidine

CAS: 100898-63-3

5'-O-DMT-N4-Ac-dC

CAS: 100898-63-3

5'-O-DMT-N4-Ac-dC, or compound 7, is a deoxynucleoside for making dod-DNA with hydrophobic regions.

• Formula: C₃₂H₃₃N₃O₇
• Color and Shape: Liquid
• Molecular weight: 571.62

N4-Acetyl-2'-deoxy-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-cytidine

CAS: 100898-63-3

N4-Acetyl-2'-deoxy-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-cytidine is a novel anticancer agent that is modified with a phosphoramidite. It is a …

• Formula: C₃₂H₃₃N₃O₇
• Purity: Min. 98 Area-%
• Molecular weight: 571.62 g/mol

N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine

CAS: 100898-63-3

N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine is a potent and selective inhibitor of the receptor tyrosine kinases Cck-A, which is …

• Formula: C₃₂H₃₃N₃O₇
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 571.62 g/mol