CAS 1009119-65-6: Daclatasvir dihydrochloride

Description: Daclatasvir dihydrochloride is an antiviral medication primarily used in the treatment of hepatitis C virus (HCV) infections. It functions as a direct-acting antiviral agent, specifically an NS5A inhibitor, which interferes with the viral replication process. The substance is characterized by its white to off-white crystalline powder form and is soluble in water, making it suitable for formulation in various dosage forms. Daclatasvir dihydrochloride has a molecular formula that reflects its complex structure, which includes multiple functional groups that contribute to its pharmacological activity. The compound is typically administered in combination with other antiviral agents to enhance efficacy and reduce the likelihood of resistance development. Its pharmacokinetics indicate a relatively long half-life, allowing for once-daily dosing in clinical settings. As with many medications, potential side effects may include fatigue, headache, and gastrointestinal disturbances, necessitating careful monitoring during treatment. Overall, Daclatasvir dihydrochloride represents a significant advancement in the management of hepatitis C, contributing to improved cure rates in affected populations.

Formula: C₄₀H₅₀N₈O₆·2ClH

InChI: InChI=1S/C40H50N8O6.2ClH/c1-23(2)33(45-39(51)53-5)37(49)47-19-7-9-31(47)35-41-21-29(43-35)27-15-11-25(12-16-27)26-13-17-28(18-14-26)30-22-42-36(44-30)32-10-8-20-48(32)38(50)34(24(3)4)46-40(52)54-6;;/h11-18,21-24,31-34H,7-10,19-20H2,1-6H3,(H,41,43)(H,42,44)(H,45,51)(H,46,52);2*1H/t31-,32-,33-,34-;;/m0../s1

InChI key: InChIKey=BVZLLUDATICXCI-JMSCDMLISA-N

SMILES: Cl.O=C(OC)NC(C(=O)N1CCCC1C2=NC=C(N2)C=3C=CC(=CC3)C=4C=CC(=CC4)C5=CN=C(N5)C6N(C(=O)C(NC(=O)OC)C(C)C)CCC6)C(C)C

Synonyms:

• Bms 790052-05
• Carbamic acid, N,N′-[[1,1′-biphenyl]-4,4′-diylbis[1H-imidazole-5,2-diyl-(2S)-2,1-pyrrolidinediyl[(1S)-1-(1-methylethyl)-2-oxo-2,1-ethanediyl]]]bis-, C,C′-dimethyl ester, hydrochloride (1:2)
• Daclatasvir dihydrochloride
• Daclatasvir.2HCL
• Daklinza
• N,N'-[[1,1'-Biphenyl]-4,4'-diylbis[1H-imidazole-5,2-diyl-(2S)-2,1-pyrrolidinediyl[(1S)-1-(1-methylethyl)-2-oxo-2,1-ethanediyl]]]biscarbamic acid dimethyl ester hydrochloride

Carbamic acid, N,N'-[[1,1'-biphenyl]-4,4'-diylbis[1H-imidazole-5,2-diyl-(2S)-2,1-pyrrolidinediyl[(1S)-1-(1-methylethyl)-2-oxo-2,1-ethanediyl]]]bis-, C,C'-dimethyl ester, hydrochloride (1:2)

CAS: 1009119-65-6

• Formula: C₄₀H₅₂Cl₂N₈O₆
• Purity: %
• Color and Shape: Solid
• Molecular weight: 811.7969

Daclatasvir DiHCl

CAS: 1009119-65-6

• Formula: C₄₀H₅₀N₈O₆HCl
• Color and Shape: Pink Solid
• Molecular weight: 738.89 2*36.46

Daclatasvir dihydrochloride

CAS: 1009119-65-6

Daclatasvir dihydrochloride is an oral antiviral that treats chronic hepatitis C by inhibiting HCV's NS5A; …

• Formula: C₄₀H₅₂Cl₂N₈O₆
• Purity: 99.84%
• Color and Shape: Solid
• Molecular weight: 811.8

Daclatasvir Dihydrochloride

CAS: 1009119-65-6

Applications Daclatasvir Dihydrochloride is an anti-hepatitis C drug. References Song, B., et. al.: Zhongguo Xinyao …

• Formula: C₄₀H₅₀N₈O₆HCl
• Color and Shape: Neat
• Molecular weight: 811.8

Daclatasvir dihydrochloride

CAS: 1009119-65-6

Daclatasvir is a direct-acting antiviral agent that inhibits the activity of the NS5A protein, which …

• Formula: C₄₀H₅₀N₈O₆·2HCl
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 811.8 g/mol