CAS 100929-50-8

(D-ala2)-methionine enkephalinamide*acetate

Description:

(D-Ala2)-methionine enkephalinamide acetate, with the CAS number 100929-50-8, is a synthetic peptide that belongs to the class of enkephalins, which are endogenous opioid peptides. This compound is characterized by its specific amino acid sequence, which includes D-alanine at the second position and methionine at the fifth position, contributing to its biological activity. It is known for its role in modulating pain and has potential applications in pain management and neuropharmacology. The acetate salt form enhances its solubility and stability, making it suitable for various experimental and therapeutic uses. As a peptide, it exhibits properties typical of such compounds, including susceptibility to enzymatic degradation and a relatively short half-life in biological systems. Its mechanism of action primarily involves binding to opioid receptors, influencing neurotransmitter release and pain perception pathways. Overall, (D-Ala2)-methionine enkephalinamide acetate represents a significant interest in research related to pain relief and opioid receptor pharmacology.

Formula: C₂₈H₃₈N₆O₆S

Synonyms:

• (D-Ala2,D-Met5)-Enkephalin
• H-Tyr-D-Ala-Gly-Phe-D-Met-OH

[Dap3]-Ghrelin (Human, Rat, 1-5)

CAS: 100929-50-8

Dap3-Ghrelin is a Ghrelin related peptide and is the active fragment of Ghrelin that binds to Ghrelin receptors with high affinity and activates the same signaling pathway as endogenous ghrelin. This product can be used in the study of obesity as Ghrelin has been shown to be a hormone that stimulates appetite and meal initiation. It could also play a role in gaining a further understanding into diabetes as Ghrelin has been found to stimulate insulin release.

Formula: C₃₁H₅₁N₇O₇

Purity: Min. 95%

Molecular weight: 633.79 g/mol

Ref: 3D-PGH-3681-PI

[D-Ala2,Met5]-Enkephalinamide

CAS: 100929-50-8

D-Ala2,Met5]-Enkephalinamide is a potent endogenous opioid peptide that binds to opioid receptors and has been shown to have both antinociceptive and depressant effects. It has been shown to be effective in a model system of pain, acting on the descending antinociceptive pathway from the rostral ventromedial medulla (RVM) to the spinal cord. D-Ala2,Met5]-Enkephalinamide has also been observed to inhibit locomotor activity in CD1 mice at sub-effective doses. D-Ala2,Met5]-Enkephalinamide has been shown to act through activation of both G protein-coupled mu opioids receptors and G protein-coupled delta opioid receptors.

Formula: C₂₈H₃₈N₆O₆S•CH₃COOH•H₂O

Purity: Min. 95%

Molecular weight: 664.77 g/mol

Ref: 3D-PEK-4117