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CAS 100929-52-0

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(D-trp11)-neurotensin

Description:
(D-Trp^11)-neurotensin is a synthetic analog of the neuropeptide neurotensin, which plays a significant role in various physiological processes, including the modulation of pain, regulation of body temperature, and influence on the endocrine system. This compound is characterized by its specific amino acid sequence, which includes a substitution of D-tryptophan at the 11th position, enhancing its stability and receptor binding affinity compared to the natural form. The molecular structure of (D-Trp^11)-neurotensin allows it to interact with neurotensin receptors, which are G-protein coupled receptors involved in neurotransmission. This peptide exhibits potential therapeutic applications, particularly in the treatment of conditions such as schizophrenia and obesity, due to its effects on dopaminergic pathways and appetite regulation. Additionally, (D-Trp^11)-neurotensin is studied for its role in neurobiology and pharmacology, making it a valuable compound in research settings. Its CAS number, 100929-52-0, is used for identification in chemical databases and regulatory contexts.
Formula:C80H122N22O19
Synonyms:
  • Pyr-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-D-Trp-Ile-Leu-OH
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