HPH-15, with the CAS number 1009838-93-0, is a chemical compound that has garnered interest in various fields, particularly in research and development. While specific characteristics can vary based on its formulation and application, HPH-15 is generally recognized for its unique structural properties that may contribute to its functionality in specific applications, such as in pharmaceuticals or materials science. It may exhibit characteristics such as solubility in certain solvents, stability under various conditions, and potential reactivity with other chemical species. The compound's molecular structure likely influences its physical properties, including melting point, boiling point, and density. Additionally, HPH-15 may have specific biological activities or interactions that make it relevant in medicinal chemistry or biochemistry. For precise applications and safety information, consulting material safety data sheets (MSDS) and peer-reviewed literature is essential, as these resources provide detailed insights into handling, toxicity, and environmental impact.

HPH-15 is an antifibrotic compound and AMPK activator.1,2 It inhibits TGF-β1-induced collagen, fibronectin 1, and connective tissue growth factor (CTGF) production in primary human dermal fibroblasts when used at a concentration of 3 µM.1 HPH-15 (10 µM) increases AMPK activation, glucose uptake, and membrane translocation of glucose transporter 4 (Glut4) in L6 rat myocytes expressing the human transporter.2 It inhibits glucose-induced triglyceride production in HepG2 cells when used at a concentration of 50 µM. In vivo, HPH-15 (10 mg/kg) reduces blood glucose levels, increases AMPK activation, and suppresses hepatic fibrosis and lipid accumulation in mice fed a high-fat diet. It also decreases dermal thickness and inflammatory cell infiltration in a mouse model of fibrosis induced by bleomycin (Item No. 13877).1WARNING This product is not for human or veterinary use.

HPH-15

1009838-93-0: HPH-15, with the CAS number 1009838-93-0, is a chemical compound that has garnered interest in various fields, particularly in research and development. While specific characteristics can vary based on its formulation and application, HPH-15 is generally recognized for its unique structural properties that may contribute to its functionality in specific applications, such as in pharmaceuticals or materials science. It may exhibit characteristics such as solubility in certain solvents, stability under various conditions, and potential reactivity with other chemical species. The compound's molecular structure likely influences its physical properties, including melting point, boiling point, and density. Additionally, HPH-15 may have specific biological activities or interactions that make it relevant in medicinal chemistry or biochemistry. For precise applications and safety information, consulting material safety data sheets (MSDS) and peer-reviewed literature is essential, as these resources provide detailed insights into handling, toxicity, and environmental impact.

<p>HPH-15 is an anti-cell migration compound that inhibits cell movement by binding to hnRNP U or suppressing TGF-β. Additionally, it prevents epithelial-to-mesenchymal transition (EMT). HPH-15 holds potential for research in areas such as anti-tumor metastasis and anti-fibrosis.</p>

CAS 1009838-93-0

HPH-15

HPH-15

Ref: TM-T205327