CAS 101-26-8

Pyridostigmine bromide

Description:

Pyridostigmine bromide is a synthetic compound classified as a reversible inhibitor of the enzyme acetylcholinesterase, which plays a crucial role in the breakdown of the neurotransmitter acetylcholine. This compound is primarily used in the treatment of myasthenia gravis, a neuromuscular disorder characterized by weakness in the skeletal muscles. Pyridostigmine bromide enhances communication between nerves and muscles by increasing acetylcholine levels at the neuromuscular junction, thereby improving muscle strength and endurance. It is typically administered orally and is known for its relatively long duration of action compared to other similar agents. The compound appears as a white to off-white crystalline powder and is soluble in water, making it suitable for various formulations. Additionally, it has been studied for its potential use in counteracting the effects of nerve agents and as a prophylactic treatment in certain military contexts. As with any medication, it may have side effects, including gastrointestinal disturbances and increased salivation, necessitating careful monitoring during use.

Formula: C₉H₁₃N₂O₂·Br

InChI: InChI=1S/C9H13N2O2.BrH/c1-10(2)9(12)13-8-5-4-6-11(3)7-8;/h4-7H,1-3H3;1H/q+1;/p-1

InChI key: InChIKey=VNYBTNPBYXSMOO-UHFFFAOYSA-M

SMILES: O(C(N(C)C)=O)C1=C[N+](C)=CC=C1.[Br-]

Synonyms:

• 1-Methyl-3-hydroxypyridinium bromide dimethylcarbamate
• 3-(Dimethylcarbamyloxy)-1-methylpyridinium bromide
• 3-Dimethylcarbamoyloxy-1-Methylpyridinium Bromide
• 3-Hydroxy-1-methylpyridinium bromide, dimethylcarbamate
• 3-[[(Dimethylamino)carbonyl]oxy]-1-methylpyridinium bromide
• Carbamic acid, dimethyl-, ester with 3-hydroxy-1-methylpyridinium bromide
• Kalimin
• Kalymin
• Mestinon
• Mestinon bromide
• NSC 679759
• Piridostigmin
• Piridostigmin bromide
• Pyridinium, 3-[[(dimethylamino)carbonyl]oxy]-1-methyl-, bromide
• Pyridinium, 3-[[(dimethylamino)carbonyl]oxy]-1-methyl-, bromide (1:1)
• Pyridinium, 3-hydroxy-1-methyl-, bromide, dimethylcarbamate
• Pyridostigmine Bromine
• Regonol

Pyridostigmine Bromide

CAS: 101-26-8, 155-97-5

Formula: C₉H₁₃BrN₂O₂

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 261.12

Ref: 3B-P1339

PYRIDOSTIGMINE BROMIDE CRS

CAS: 101-26-8

PYRIDOSTIGMINE BROMIDE CRS

Formula: C₉H₁₃BrN₂O₂

Color and Shape: Crystalline Powder. White. Powder.

Molecular weight: 261.1157

Ref: 41-P4099900

PYRIDOSTIGMINE BROMIDE RS

CAS: 101-26-8

PYRIDOSTIGMINE BROMIDE RS

Formula: C₉H₁₃BrN₂O₂

Molecular weight: 261.1157

Ref: 41-ICRS0405

Pyridostigmine bromide

CAS: 101-26-8

Pyridostigmine bromide

Formula: C₉H₁₃BrN₂O₂

Color and Shape: White

Molecular weight: 261.1157

Ref: 47-1033

Pyridostigmine Bromide

CAS: 101-26-8

Compounds containing an unfused pyridine ring in the structure, nesoi

Formula: C₉H₁₃BrN₂O₂

Color and Shape: White Off-White Powder

Molecular weight: 260.01604

Ref: 45-1586009

3-(Dimethylcarbamoyloxy)-1-Methylpyridinium Bromide

CAS: 101-26-8

Formula: C₉H₁₃BrN₂O₂

Purity: %

Color and Shape: Solid

Molecular weight: 261.1157

Ref: IN-DA0033GW

Pyridostigmine bromide

CAS: 101-26-8

Pyridostigmine bromide (Mestinon), a cholinesterase inhibitor, is used in the treatment of myasthenia gravis and to reverse the actions of muscle relaxants.

Formula: C₉H₁₃BrN₂O₂

Purity: 99.00% - 99.98%

Color and Shape: White Or Practically White Crystalline Powder Pale Yellow To Colorless Liquid

Molecular weight: 261.12

Ref: TM-T0780

Pyridostigmine bromide

CAS: 101-26-8

Pyridostigmine bromide

Purity: ≥95%

Molecular weight: 261.12g/mol

Ref: 54-BUP18860

Pyridostigmine Bromide

CAS: 101-26-8

Formula: C₉H₁₃N₂O₂·Br

Color and Shape: White To Off-White Solid

Molecular weight: 181.22 79.90

Ref: 4Z-P-621

Pyridostigmine Bromide

Controlled Product

CAS: 101-26-8

Formula: C₉H₁₃N₂O₂·Br

Color and Shape: Neat

Molecular weight: 261.12

Ref: 86-MM0429.00

Pyridostigmine bromide

CAS: 101-26-8

Formula: C₉H₁₃BrN₂O₂

Purity: 98.5 - 101.5 % (dried basis)

Color and Shape: White to off-white crystalline powder

Molecular weight: 261.12

Ref: 7W-GP7135

Pyridostigmine Bromide

Controlled Product

CAS: 101-26-8

Stability Hygroscopic
Applications Cholinergic, used in the treatment of myasthenia gravis, and is a pre-exposure antidote to chemical warfare agents.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kayihan, G., et al.: Toxicol. Environ. Chem., 92, 1783 (2010), Yu, Q., et al.: Bioorg. Med. Chem., 18, 4687 (2010), Voicu, V., et al.: J. Pharm. Biomed. Anal., 52, 508 (2010),

Formula: C₉H₁₃N₂O₂·Br

Color and Shape: White

Molecular weight: 261.12

Ref: TR-P991705

Pyridostigmine bromide

Controlled Product

CAS: 101-26-8

Pyridostigmine bromide is a cholinergic drug that inhibits the enzyme acetylcholinesterase in the central and peripheral nervous systems. This inhibition leads to an increase in the neurotransmitter acetylcholine, which has an anti-inflammatory effect on cytokine production. Pyridostigmine bromide is used to treat gastrointestinal disorders, such as bowel disease. It also has been shown to be effective against infectious diseases, such as tuberculosis, because of its ability to inhibit proinflammatory cytokines such as IL-10 and TNF-α. Pyridostigmine bromide can be used as an experimental model for inflammatory bowel disease because it is minimally toxic and does not have any phase transition temperature in the human serum.

Formula: C₉H₁₃BrN₂O₂

Color and Shape: Powder

Molecular weight: 261.12 g/mol

Ref: 3D-FP27317

Pyridostigmine bromide

Controlled Product

CAS: 101-26-8

Pyridostigmine bromide is a versatile building block and a reagent for research chemicals. It is also used as a speciality chemical in the synthesis of other compounds, such as pesticides. Pyridostigmine bromide is a high-quality product that has many uses in the chemical industry. It can be used as an intermediate in organic synthesis, or it can be converted to pyridostigmine sulfate, which is used to treat myasthenia gravis. This compound is also useful because it can serve as a scaffold for the design of new pharmaceuticals.

Formula: C₉H₁₃BrN₂O₂

Molecular weight: 261.12 g/mol

Ref: 3D-Q-201644

3-[(dimethylcarbamoyl)oxy]-1-methylpyridin-1-ium bromide

CAS: 101-26-8

Formula: C₉H₁₃BrN₂O₂

Purity: 99+%

Molecular weight: 261.119

Ref: 10-F358103

Pyridostigmine-d3 Bromide (1-methyl-d3)

Controlled Product

CAS: 101-26-8

Applications Pyridostigmine-d3 Bromide (1-methyl-d3) is a useful isotopically labeled compound of Pyridostigmine Bromide (P991705)

Formula: C₉D₃H₁₀N₂O₂·Br

Color and Shape: Neat

Molecular weight: 264.14

Ref: TR-P991706

Pyridostigmine Bromide

CAS: 101-26-8

Formula: C₉H₁₃N₂O₂Br

Molecular weight: 181.21 : 79.9

Ref: ST-EA-CP-P57003