CAS 101-31-5

(-)-Atropine

Description:

(-)-Atropine is a tropane alkaloid derived from plants of the Solanaceae family, particularly from belladonna (Atropa belladonna) and other related species. It is characterized by its chiral nature, existing as a single enantiomer, which is the (-)-form, known for its pharmacological activity. Atropine is a tertiary amine with a molecular formula of C17H23NO3 and a molecular weight of approximately 289.37 g/mol. It is a colorless to pale yellow crystalline solid that is soluble in organic solvents like alcohol and chloroform but has limited solubility in water. Atropine acts primarily as an anticholinergic agent, blocking the action of acetylcholine at muscarinic receptors, which leads to effects such as increased heart rate, dilation of pupils, and reduced secretions. It is used clinically to treat bradycardia, as an antidote for organophosphate poisoning, and to induce mydriasis during ophthalmic examinations. Due to its potent effects, atropine must be used with caution, as it can cause side effects such as dry mouth, blurred vision, and tachycardia.

Formula: C₁₇H₂₃NO₃

InChI: InChI=1S/C17H23NO3/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3/t13-,14+,15+,16-/m1/s1

InChI key: InChIKey=RKUNBYITZUJHSG-FXUDXRNXSA-N

SMILES: O(C([C@H](CO)C1=CC=CC=C1)=O)[C@@H]2C[C@]3(N(C)[C@@](C2)(CC3)[H])[H]

Synonyms:

• (-)-Atropine
• (1R,5S)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl (2S)-3-hydroxy-2-phenylpropanoate
• (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl (2S)-3-hydroxy-2-phenylpropanoate
• (S)-(-)-Hyoscyamine
• (S)-Atropine
• 1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-Tropan-3α-ol, (-)-tropate (ester)
• 1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-Tropan-3α-yl (-)-tropate
• 1αH,5αH-Tropan-3α-ol, (-)-tropate (ester)
• 1αH,5αH-Tropan-3α-yl (-)-tropate
• 8-Methyl-8-Azabicyclo[3.2.1]Oct-3-Yl 3-Hydroxy-2-Phenylpropanoate
• 8-methyl-8-azabicyclo[3.2.1]oct-3-yl (2S)-3-hydroxy-2-phenylpropanoate
• <span class="text-smallcaps">L</span>-Hyoscyamin
• <span class="text-smallcaps">L</span>-Hyoscyamine
• Benzeneacetic acid, α-(hydroxymethyl)-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, (αS)-
• Benzeneacetic acid, α-(hydroxymethyl)-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, [3(S)-endo]-
• Cystospaz
• Daturine
• Duboisine
• Hiosciamina
• Hyoscyamin
• L-Hyoscyamin
• L-Hyoscyamine
• L-Hyoscyamine free base
• Tropic acid, 1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-tropan-3α-yl ester, (-)-
• l-Atropine
• l-Tropine tropate

L-Hyoscyamine

CAS: 101-31-5

L-Hyoscyamine analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Formula: C₁₇H₂₃NO₃

Purity: (HPLC) ≥90%

Color and Shape: Powder

Molecular weight: 289.38

Ref: 11-0669

Hyoscine Hydrobromide EP impurity A

CAS: 101-31-5

Formula: C₁₇H₂₃NO₃

Molecular weight: 289.4

Ref: ST-EA-CP-H16001

Hyoscyamine

CAS: 101-31-5

Color and Shape: Neat

Ref: 61-FOR1699.00

(-)-Atropine

CAS: 101-31-5

Formula: C₁₇H₂₃NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 289.3694

Ref: IN-DA0003FJ

L-Hyoscyamine

CAS: 101-31-5

L-Hyoscyamine (Daturine) functions as a non-selective, competitive antagonist of muscarinic receptors, thereby inhibiting the parasympathetic activities.

Formula: C₁₇H₂₃NO₃

Purity: 99.71% - 99.81%

Color and Shape: White Crystalline Powder

Molecular weight: 289.37

Ref: TM-T0962

Scopolamine EP Impurity D (Hyoscine Hydrobromide EP Impurity A, Hyoscyamine, L-Atropine )

CAS: 101-31-5

Formula: C₁₇H₂₃NO₃

Color and Shape: White To Off-White Solid

Molecular weight: 289.38

Ref: 4Z-S-0121

Hyoscyamine

CAS: 101-31-5

Formula: C₁₇H₂₃NO₃

Molecular weight: 289.38

Ref: 7W-GY3235

Hyoscyamine

CAS: 101-31-5

Formula: C₁₇H₂₃NO₃

Purity: 95%~99%

Molecular weight: 289.375

Ref: BP-BP0749

Hyoscyamine

Controlled Product

CAS: 101-31-5

Formula: C₁₇H₂₃NO₃

Color and Shape: Neat

Molecular weight: 289.37

Ref: 04-C14270500

Hyoscyamine

Controlled Product

CAS: 101-31-5

Formula: C₁₇H₂₃NO₃

Color and Shape: Neat

Molecular weight: 289.37

Ref: 86-MM1699.00

L-Atropine-d5

CAS: 101-31-5

Formula: C₁₇H₁₈D₅NO₃

Molecular weight: 294.41

Ref: 4Z-A-151028

(-)-Hycosamine-d3

Controlled Product

CAS: 101-31-5

Applications (-)-Hycosamine-d3, is the labeled analogue of (-)-Hycosamine (H674300), a natural compound that has inhibitory activity against cholinesterases.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Brunhofer, G. et al.: Bioorg. Med. Chem., 20, 6669 (2012);

Formula: C₁₇D₃H₂₀NO₃

Color and Shape: Off-White

Molecular weight: 292.39

Ref: TR-H674302

(-)-Hycosamine

Controlled Product

CAS: 101-31-5

Applications (-)-Hycosamine is a natural compound that has inhibitory activity against cholinesterases.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Brunhofer, G., et al.: Bioorg. Med. Chem., 20, 6669 (2012);

Formula: C₁₇H₂₃NO₃

Color and Shape: Neat

Molecular weight: 289.37

Ref: TR-H674300

Scopolamine EP Impurity D (Hyoscine Hydrobromide EP Impurity A, Hyoscyamine, L-Atropine )

CAS: 101-31-5

Formula: C₁₇H₂₃NO₃

Molecular weight: 289.38

Ref: ST-EA-CP-S114019

Hyoscyamine

CAS: 101-31-5

Hyoscyamine is a tropane alkaloid that is found in plants of the Solanaceae family, such as henbane and jimson weed. It has been used for centuries to treat gastrointestinal disorders, spastic colon, urinary incontinence, and other conditions. The drug works by inhibiting the release of acetylcholine from nerve endings at synapses in the brain and along the gastrointestinal tract. Inhibition of acetylcholine release leads to an increase in parasympathetic activity which results in decreased motility and increased secretions. Hyoscyamine inhibits epoxidase activity, which may be associated with its anti-inflammatory properties. This drug also has transcriptional regulation effects on genes related to growth, development, and reproduction; it inhibits the synthesis of proteins that regulate cell growth and division. Scopolamine is a derivative of hyoscyamine that has been used as a sedative or preoperative medication to reduce saliva production and decrease bronchial

Formula: C₁₇H₂₃NO₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 289.37 g/mol

Ref: 3D-FH36337