CAS 101012-12-8

2-Chloro-1,3-thiazole-5-carboxylic acid

Description:

2-Chloro-1,3-thiazole-5-carboxylic acid is a heterocyclic compound characterized by the presence of a thiazole ring, which is a five-membered ring containing both sulfur and nitrogen atoms. The compound features a carboxylic acid functional group (-COOH) and a chlorine substituent at the second position of the thiazole ring. This structure imparts unique chemical properties, including potential acidity due to the carboxylic acid group and reactivity associated with the chlorine atom. The thiazole moiety contributes to its biological activity, making it of interest in pharmaceutical and agrochemical research. The compound is typically a solid at room temperature and may exhibit moderate solubility in polar solvents. Its synthesis often involves the reaction of thiazole derivatives with chlorinating agents and subsequent carboxylation. Due to its functional groups, 2-Chloro-1,3-thiazole-5-carboxylic acid can participate in various chemical reactions, including nucleophilic substitutions and coupling reactions, making it a versatile intermediate in organic synthesis.

Formula: C₄H₂ClNO₂S

InChI: InChI=1/C4H2ClNO2S/c5-4-6-1-2(9-4)3(7)8/h1H,(H,7,8)

InChI key: InChIKey=HNJOKQPEJIWTRF-UHFFFAOYSA-N

SMILES: C(O)(=O)C=1SC(Cl)=NC1

Synonyms:

• 2-Chloro-5-thiazolecarboxylic acid
• 2-Chlorothiazole-5-Carboxylic Acid
• 2-Chlorothiazole-5-Carboxylicacid
• 5-Thiazolecarboxylic acid, 2-chloro-
• 2-Chloro-1,3-thiazole-5-carboxylic acid
• 5-Carboxy-2-chloro-1,3-thiazole
• 2-chloro-thiazol-5-carboxylic acid
• 5-Thiazolecarboxylicacid, 2-chloro-
• 2-Chloro-1,3-thiazole-5-carboxylic acid 97%
• 2-Chloro-5-carboxy-1,3-thiazole
• 2-Chloro-1,3-thiazole-5-carboxylic acid, >=98%

5-Thiazolecarboxylic acid, 2-chloro-

CAS: 101012-12-8

Formula: C₄H₂ClNO₂S

Purity: 97%

Color and Shape: Solid

Molecular weight: 163.5822

Ref: IN-DA0003JK

2-Chloro-1,3-thiazole-5-carboxylic acid

CAS: 101012-12-8

2-Chloro-1,3-thiazole-5-carboxylic acid

Formula: C₄H₂ClNO₂S

Purity: 97%

Color and Shape: off-white crystalline solid

Molecular weight: 163.58g/mol

Ref: 54-OR14876

2-Chloro-5-thiazolecarboxylic Acid-13C3,15N

Controlled Product

CAS: 101012-12-8

Formula: CC₃H₂ClNO₂S

Color and Shape: Neat

Molecular weight: 167.55

Ref: TR-C411468

2-Chloro-1,3-thiazole-5-carboxylic Acid

CAS: 101012-12-8

Applications 2-Chloro-5-thiazolecarboxylic Acid (C411465) was studied as one of the metabolites of thiamethoxam, clothianidin, and dinotefuran in mice.
References Ford, K., et al.: Chem. Res. Toxicol., 19, 1549 (2006);

Formula: C₄H₂ClNO₂S

Color and Shape: Neat

Molecular weight: 163.582

Ref: TR-C411465

2-Chloro-1,3-thiazole-5-carboxylic acid

CAS: 101012-12-8

Formula: C₄H₂ClNO₂S

Purity: 95%

Color and Shape: Solid

Molecular weight: 163.58

Ref: 10-F066176

2-Chloro-5-thiazolecarboxylic Acid-13C3,15N

CAS: 101012-12-8

2-Chloro-5-thiazolecarboxylic Acid-13C3,15N is a neonicotinoid pesticide that inhibits the function of acetylcholinesterase. It has been used as an analytical method for detecting neonicotinoids in human urine and has been shown to interact with glutamate in the body. 2-Chloro-5-thiazolecarboxylic Acid-13C3,15N is also used to control pests on plants. This compound has been found to be effective against a number of insects, including aphids, leafhoppers, thrips, and whiteflies. 2-Chloro-5-thiazolecarboxylic Acid-13C3,15N can be applied to plant tissue or seedlings orally or by spraying onto leaves or stems. This compound can also be applied as a soil drench or seed treatment. The compound can then be recovered from plant tissues using el

Formula: C₄H₂ClNO₂S

Purity: Min. 95%

Molecular weight: 167.55 g/mol

Ref: 3D-BEA01212