CAS 101020-89-7
:artemisitene
Description:
Artemisitene is a sesquiterpene lactone derived from the plant Artemisia annua, commonly known as sweet wormwood. It is notable for its potential therapeutic properties, particularly in the context of antimalarial activity. The compound exhibits a unique structure characterized by a bicyclic framework, which contributes to its biological activity. Artemisitene has been studied for its ability to interact with various biological targets, potentially leading to the development of new treatments for malaria and other diseases. Its mechanism of action is thought to involve the generation of reactive oxygen species, which can damage the cellular components of parasites. Additionally, artemisitene may possess anti-inflammatory and anticancer properties, making it a subject of interest in pharmacological research. The compound is typically isolated through extraction and purification processes from the plant source, and its stability and solubility characteristics are important for its application in medicinal chemistry. Overall, artemisitene represents a promising avenue for further exploration in drug development and natural product chemistry.
Formula:C15H20O5
InChI:InChI=1/C15H20O5/c1-8-4-5-11-9(2)12(16)17-13-15(11)10(8)6-7-14(3,18-13)19-20-15/h8,10-11,13H,2,4-7H2,1,3H3/t8-,10+,11?,13-,14-,15-/m1/s1
Synonyms:- 3,12-Epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin-10(3H)-one, octahydro-3,6-dimethyl-9-methylene-, (3R-(3alpha,5abeta,6beta,8abeta,12beta,12aR*))-
- (3R,5aS,6R,12S,12aR)-3,6-dimethyl-9-methylideneoctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one
- Artemisitene
- Methyl Artemisinin
- 3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)-one, octahydro-3,6-dimethyl-9-methylene-, (3R,5aS,6R,8aS,12S,12aR)-
- Artemisiten
- (3R,5aS,6R,8aS,12S,12aR)-Octahydro-3,6-diMethyl-9-Methylene-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)-one
- ArteMisitene (Methyl ArteMisinin)
- Dehydroqinghaosu
- Artemisinin and Piperaquine Tablets Impurity Ⅰ:(artemisitene)(3R,5aS,6R,8aS,12S,12aR)-Octahydro-3,6-diMethyl-9-Methylene-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)-oneChemicalBook
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Found 9 products.
Artemisitene (Methyl Artemisinin)
CAS:Formula:C15H20O5Color and Shape:White To Off-White SolidMolecular weight:280.32Artemisitene
CAS:<p>Artemisitene, an oxidized antimalarial derivative of Artemisinin, stems from precursors like Artemisinin B and Artemisinic acid.</p>Formula:C15H20O5Purity:99.58%Color and Shape:SolidMolecular weight:280.32Artemisitene
CAS:<p>Applications Artemisitene, the oxidized form of Artemisinin (A777500), exists as a minor constituent in an American variant of Artemisia annua. Artemisinin precursors are the important basic substances for biosynthesis of Artemisinin, including Artemisinic acid, Artemisinin B, Artemisitene, etc. An antimalarial agent.<br>References Li, Y., et al.: Curr. Med. Chem., 10, 2197 (2003), Marrero-Ponce, Y., et al.: Bioorg. Med. Chem., 13, 1293 (2005), McMichael, A., et al.: Lancet, 367, 859 (2006),<br></p>Formula:C15H20O5Color and Shape:NeatMolecular weight:280.329-Methylene-13C-D2 Artemisitene
CAS:Controlled ProductFormula:CC14D2H18O5Color and Shape:NeatMolecular weight:283.321Artemisitene
CAS:<p>Artemisitene is a sesquiterpene lactone that has been used as an anti-infective agent. It has shown cytotoxic activity against human lung cells, and also inhibits the growth of human cervical cancer cells in tissue culture. Artemisitene is metabolized to artemisinin, which is the active form that binds to DNA and blocks cellular replication. Artemisitene's cytotoxic activity is due to its ability to inhibit the synthesis of DNA, RNA, and proteins by binding to ribosomes. Artemisitene can be administered orally or intravenously and shows good bioavailability following oral administration.</p>Formula:C15H20O5Purity:Min. 95%Color and Shape:PowderMolecular weight:280.32 g/mol
