CAS 101053-34-3

Pyrrolo[2,3-b]indol-3a(1H)-ol,2,3,8,8a-tetrahydro-1-methyl-, (3aR,8aS)-

Description:

Pyrrolo[2,3-b]indol-3a(1H)-ol, 2,3,8,8a-tetrahydro-1-methyl-, (3aR,8aS)- is a complex organic compound characterized by its bicyclic structure, which includes a pyrrole and an indole moiety. This compound features a tetrahydro configuration, indicating the presence of four hydrogenated carbon atoms in its ring system. The specific stereochemistry, denoted by (3aR,8aS), suggests that it has distinct spatial arrangements of its atoms, which can influence its biological activity and interactions. The hydroxyl group (-OH) at the 3-position contributes to its potential as a hydrogen bond donor, while the methyl group at the 1-position may affect its lipophilicity and solubility. This compound is of interest in medicinal chemistry and pharmacology due to its structural similarity to various bioactive molecules, potentially exhibiting neuroactive or therapeutic properties. Its CAS number, 101053-34-3, allows for precise identification in chemical databases and literature. Overall, the unique structural features of this compound make it a subject of interest for further research and application in various fields.

Formula: C₁₁H₁₄N₂O

InChI: InChI=1S/C11H14N2O/c1-13-7-6-11(14)8-4-2-3-5-9(8)12-10(11)13/h2-5,10,12,14H,6-7H2,1H3/t10-,11+/m0/s1

InChI key: InChIKey=CBQYNPHHHJTCJS-WDEREUQCSA-N

SMILES: O[C@]12C=3C(N[C@]1(N(C)CC2)[H])=CC=CC3

Synonyms:

• (3aR,8aS)-2,3,8,8a-Tetrahydro-1-methylpyrrolo[2,3-b]indol-3a(1H)-ol
• Alline
• Pyrrolo[2,3-b]indol-3a(1H)-ol,2,3,8,8a-tetrahydro-1-methyl-, (3aR-cis)-
• Pyrrolo[2,3-b]indol-3a(1H)-ol, 2,3,8,8a-tetrahydro-1-methyl-, (3aR,8aS)-

Alline

Controlled Product

CAS: 101053-34-3

Formula: C₁₁H₁₄N₂O

Color and Shape: Neat

Molecular weight: 190.242

Ref: TR-A533430

Alline

CAS: 101053-34-3

Alline is an anticancer drug that contains inhibitors of capsaicin, a protein that has been shown to promote tumor growth. This drug acts as an analog of capsaicin and has been found in urine samples of cancer patients. Alline works by inhibiting kinases, which are enzymes involved in the regulation of cell growth and proliferation. It induces apoptosis, or programmed cell death, in cancer cells by disrupting the signaling pathways that promote cancer cell survival. Alline has been tested on human cancer cells and has shown promising results in inhibiting tumor growth. Additionally, it has also been tested on Chinese hamster ovary cells with similar effects. This drug may represent a new approach to treating cancer with fewer side effects than traditional chemotherapy drugs.

Formula: C₁₁H₁₄N₂O

Purity: Min. 95%

Molecular weight: 190.24 g/mol

Ref: 3D-BEA05334