CAS 1011-92-3

α-Cyanocinnamic acid

Description:

α-Cyanocinnamic acid, with the CAS number 1011-92-3, is an organic compound characterized by its distinctive structure, which includes a cyanide group (-CN) and a trans-alkene configuration. This compound typically appears as a crystalline solid and is known for its aromatic properties due to the presence of a phenyl group. It is soluble in organic solvents such as ethanol and acetone but has limited solubility in water. α-Cyanocinnamic acid is notable for its role in organic synthesis, particularly in the formation of various derivatives through reactions such as Michael addition and condensation. Additionally, it exhibits potential biological activity, making it of interest in pharmaceutical research. The compound's melting point and boiling point can vary based on purity and environmental conditions, and it should be handled with care due to the presence of the cyanide functional group, which can be toxic. Overall, α-Cyanocinnamic acid is a versatile compound with applications in both synthetic chemistry and medicinal chemistry.

Formula: C₁₀H₇NO₂

InChI: InChI=1S/C10H7NO2/c11-7-9(10(12)13)6-8-4-2-1-3-5-8/h1-6H,(H,12,13)

InChI key: InChIKey=CDUQMGQIHYISOP-UHFFFAOYSA-N

SMILES: C(=C(C(O)=O)C#N)C1=CC=CC=C1

Synonyms:

• (2E)-2-cyano-3-phenylprop-2-enoate
• (2E)-2-cyano-3-phenylprop-2-enoic acid
• (2Z)-2-cyano-3-phenylprop-2-enoic acid
• 2-Cyano-3-phenyl-2-propenoic acid
• 2-Cyano-3-phenylacrylic acid
• 2-Cyanocinnamic acid
• 2-Propenoic acid, 2-cyano-3-phenyl-
• 3-Phenyl-2-cyano-2-propenoic acid
• Benzylidene ethylcyanoacetane
• Cinnamic acid, α-cyano-
• Cyanocinnamicacid
• NSC 298
• α-Cyano-β-phenylacrylic acid

α-Cyanocinnamic Acid

CAS: 1011-92-3

Formula: C₁₀H₇NO₂

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 173.17

Ref: 3B-C0447

2-Cyano-3-phenylacrylic acid

CAS: 1011-92-3

Formula: C₁₀H₇NO₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 173.1681

Ref: IN-DA0003RC

α-cyanocinnamic acid

CAS: 1011-92-3

α-cyanocinnamic acid

Formula: C₁₀H₇NO₂

Purity: 98%

Color and Shape: white solid

Molecular weight: 173.17g/mol

Ref: 54-OR922724

α-Cyanocinnamic Acid

CAS: 1011-92-3

Purity: 98%

Molecular weight: 173.1710052

Ref: 10-F875782

a-Cyanocinnamic acid

CAS: 1011-92-3

a-Cyanocinnamic acid is a 3-hydroxycinnamic acid that can be found in coffee. It has been shown to inhibit the growth of colorectal adenocarcinoma cells and other cancer cells by binding to an inhibitor site on fatty acid synthesis enzymes, such as pyruvate carboxylase, hydroxylase, and acetyl-CoA carboxylase. This inhibition leads to decreased levels of fatty acids and increased levels of pyruvate and hydrogen peroxide, which inhibits cell proliferation. In addition, a-cyanocinnamic acid has been shown to have a hypoxic tumor selectivity index of 10.7%, which means it selectively targets tumors with low oxygen levels.

Formula: C₁₀H₇NO₂

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 173.17 g/mol

Ref: 3D-FC70296