CAS 1011529-10-4

4'-C-azido-2'-deoxy-2'-fluoro-beta-D-arabinocytidine

Description:

4'-C-azido-2'-deoxy-2'-fluoro-beta-D-arabinocytidine, identified by its CAS number 1011529-10-4, is a nucleoside analog that features a unique combination of modifications to the standard ribonucleoside structure. This compound contains an azido group at the 4' position and a fluorine atom at the 2' position of the sugar moiety, which enhances its stability and alters its biological activity. The presence of the azido group can facilitate various chemical reactions, including click chemistry, making it useful in bioconjugation applications. The fluorine substitution at the 2' position contributes to its resistance to enzymatic degradation, which is advantageous for therapeutic applications, particularly in antiviral and anticancer research. As a beta-D-arabinocytidine derivative, it retains the ability to interact with nucleic acid synthesis pathways, potentially inhibiting viral replication or tumor growth. Overall, this compound is of significant interest in medicinal chemistry and pharmacology due to its structural modifications that enhance its therapeutic potential.

4'-C-azido-2'-deoxy-2'-fluoro-β-D-arabinocytidine

CAS: 1011529-10-4

Formula: C₉H₁₁FN₆O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 286.2198

Ref: IN-DA00944T

Azvudine

CAS: 1011529-10-4

Azvudine

Purity: ≥98%

Molecular weight: 286.22g/mol

Ref: 54-BUP04779

Azvudine-13C-15N2

CAS: 1011529-10-4

Formula: C₈₁₃CH₁₁FN₄₁₅N₂O₄

Molecular weight: 289.20

Ref: 4Z-A-360011

Azvudine

CAS: 1011529-10-4

Azvudine (FNC) is a powerful NRTI effective against HIV, HBV, HCV, and resistant strains.

Formula: C₉H₁₁FN₆O₄

Purity: 99.76% - >99.99%

Color and Shape: Solid

Molecular weight: 286.22

Ref: TM-T14489

Azvudine

CAS: 1011529-10-4

Formula: C₉H₁₁FN₆O₄

Molecular weight: 286.22

Ref: 4Z-A-360010

4'-C-Azido-2'-deoxy-2'-fluoro-β-D-arabinocytidine

CAS: 1011529-10-4

4'-C-Azido-2'-deoxy-2'-fluoro-β-D-arabinocytidine (4FA) is a potent inhibitor of the growth of HIV. It has been shown to inhibit the production of inflammatory cytokines and chemokines, which are associated with inflammatory diseases such as arthritis and asthma. 4FA has also been shown to inhibit glycogen synthase kinase 3 (GSK3), which is involved in the regulation of cellular signaling pathways that control cell growth and proliferation. Furthermore, 4FA inhibits an enzyme that is needed for viral replication and can be used as a therapeutic agent against viruses such as hepatitis C virus.

Formula: C₉H₁₁FN₆O₄

Purity: Min. 95%

Color and Shape: Off-White Powder

Molecular weight: 286.22 g/mol

Ref: 3D-NA32212