CAS 101167-02-6

N-[[4-(Aminosulfonyl)phenyl]methyl]-2-chloroacetamide

Description:

N-[[4-(Aminosulfonyl)phenyl]methyl]-2-chloroacetamide, identified by its CAS number 101167-02-6, is a chemical compound characterized by its amide functional group and the presence of a chloroacetyl moiety. This compound features a phenyl ring substituted with an aminosulfonyl group, which contributes to its potential biological activity. The presence of the chlorine atom in the chloroacetamide structure enhances its reactivity, making it a candidate for various chemical reactions, including nucleophilic substitutions. The sulfonamide group is known for its role in medicinal chemistry, particularly in the development of antibacterial agents. This compound may exhibit properties such as solubility in polar solvents and potential interactions with biological targets, which could be of interest in pharmaceutical research. Its structural characteristics suggest that it may participate in hydrogen bonding and other intermolecular interactions, influencing its behavior in biological systems and its utility in drug design. Overall, N-[[4-(Aminosulfonyl)phenyl]methyl]-2-chloroacetamide represents a compound of interest in both synthetic and medicinal chemistry.

Formula: C₉H₁₁ClN₂O₃S

InChI: InChI=1S/C9H11ClN2O3S/c10-5-9(13)12-6-7-1-3-8(4-2-7)16(11,14)15/h1-4H,5-6H2,(H,12,13)(H2,11,14,15)

InChI key: InChIKey=LTZYLTKHHXTVBQ-UHFFFAOYSA-N

SMILES: S(N)(=O)(=O)C1=CC=C(CNC(CCl)=O)C=C1

Synonyms:

• 2-Chloro-N-(4-sulfamoylbenzyl)acetamide
• 2-Chloro-N-[(4-sulfamoylphenyl)methyl]acetamide
• Acetamide, 2-chloro-N-p-sulfamoylbenzyl-
• N-[[4-(Aminosulfonyl)phenyl]methyl]-2-chloroacetamide
• acetamide, N-[[4-(aminosulfonyl)phenyl]methyl]-2-chloro-
• N-[4-(aminosulfonyl)benzyl]-2-chloroacetamide

2-chloro-N-[(4-sulfamoylphenyl)methyl]acetamide

CAS: 101167-02-6

Formula: C₉H₁₁ClN₂O₃S

Color and Shape: Solid

Molecular weight: 262.7132

Ref: IN-DA0003VK

2-Chloro-N-[(4-sulfamoylphenyl)methyl]acetamide

CAS: 101167-02-6

Acetazolamide is a carbonic anhydrase inhibitor that is used to treat glaucoma, epilepsy and altitude sickness. It is also used to treat the symptoms of Ménière's disease. Acetazolamide has been shown to inhibit pentylenetetrazole-induced convulsions in rats and mice, suggesting it would be nontoxic if administered orally to humans. Acetazolamide inhibits carbonic anhydrase, which is present in the human brain at nanomolar concentrations. This inhibition results in decreased production of bicarbonate ions from carbon dioxide and water, leading to a decrease in intracranial pressure.

Formula: C₉H₁₁ClN₂O₃S

Purity: Min. 95%

Molecular weight: 262.71 g/mol

Ref: 3D-BEA16702