CAS 101204-49-3

2'-DEOXY-N6-METHYLADENOSINE 3',5'-BISPHOSPHATE TETRAAMMONIUM SALT

Description:

2'-Deoxy-N6-methyladenosine 3',5'-bisphosphate tetraammonium salt is a nucleotide analog characterized by its structural components, which include a deoxyribose sugar, a methylated adenine base, and two phosphate groups linked by phosphoanhydride bonds. This compound is often used in biochemical research, particularly in studies involving nucleic acid interactions and enzyme activity, due to its ability to mimic natural nucleotides. The tetraammonium salt form enhances its solubility in aqueous solutions, making it suitable for various laboratory applications. Its molecular structure allows it to participate in biochemical pathways, potentially influencing cellular processes. The presence of the methyl group at the N6 position of the adenine base can affect its binding affinity and specificity towards enzymes and receptors. Overall, this compound serves as a valuable tool in molecular biology and biochemistry, facilitating the exploration of nucleotide functions and interactions within biological systems.

Formula: C₁₁H₁₇N₅O₉P₂

InChI: InChI=1S/C11H17N5O9P2/c1-12-10-9-11(14-4-13-10)16(5-15-9)8-2-6(25-27(20,21)22)7(24-8)3-23-26(17,18)19/h4-8H,2-3H2,1H3,(H,12,13,14)(H2,17,18,19)(H2,20,21,22)/t6-,7+,8+/m0/s1

InChI key: InChIKey=CCPLITQNIFLYQB-XLPZGREQSA-N

SMILES: N(C)C1=C2C(N(C=N2)[C@@H]3O[C@H](COP(=O)(O)O)[C@@H](OP(=O)(O)O)C3)=NC=N1

Synonyms:

• 2'-Deoxy-N6-Methyladenosine 3',5'-Bisphosphate Tetrasodium Salt
• 3′-Adenylic acid, 2′-deoxy-N-methyl-, 5′-(dihydrogen phosphate)
• MRS2179 hydrate ammonium salt
• MRS2179tetraammoniumsalt
• Mrs 2179
• Mrs 2179 Tetrasodium Salt
• [2-[(hydroxy-oxidophosphoryl)oxymethyl]-5-(6-methylaminopurin-9-yl)oxolan-3-yl] hydrogen phosphate
• 2'-DEOXY-N6-METHYLADENOSINE 3',5'-BISPHOSPHATE TETRAAMMONIUM SALT
• MRS 2179, CID: 24867852
• MRS 2179 ammonium salt hydrate
• MRS2179 ammonium salt

2'-DEOXY-N6-METHYLADENOSINE 3',5'-BISPHOSPHATE TETRAAMMONIUM SALT

CAS: 101204-49-3

Formula: C₁₁H₁₇N₅O₉P₂

Molecular weight: 425.2283

Ref: IN-DA008Y3X

MRS 2179 ammonium salt hydrate

CAS: 101204-49-3

Formula: C₁₁H₁₇N₅O₉P₂·xNH₃·yH₂O

Molecular weight: 425.23 (anhydrous)

Ref: 7W-GK4599

MRS 2179 ammonium salt hydrate

CAS: 101204-49-3

MRS 2179 is a novel, potent and selective antagonist of the P2Y1 receptor. It inhibits intracellular Ca2+ levels and neuronal death in vitro. MRS 2179 is also an antagonist of toll-like receptor 4 (TLR4), which has been implicated in the regulation of immune responses. MRS 2179 has been shown to inhibit axonal growth and energy metabolism in vitro, as well as receptor activity.

Formula: C₁₁H₁₇N₅O₉P₂·xNH₃·yH₂O

Purity: Min. 95%

Molecular weight: 423.22 g/mol

Ref: 3D-BEA20449

MRS2179

CAS: 101204-49-3

MRS2179: P2Y1 antagonist, Kb=100 nM, inactive on P2Y2/4/6 (to 30µM), inhibits ADP-induced platelet changes, prolongs bleeding in rodents.

Formula: C₁₁H₁₇N₅O₉P₂

Color and Shape: Solid

Molecular weight: 425.23

Ref: TM-T28099