CAS 1012080-88-4

5'-Azido-2',5'-dideoxy-2'-fluorouridine

CAS: 1012080-88-4

Nucleoside Derivatives - Azido-nucleosides, 5’-Modified nucleosides, 2’-Modified nucleosides, Fluoro-modified nucleosides

Formula: C₉H₁₀FN₅O₄

Color and Shape: Solid

Molecular weight: 271.21

Ref: TM-TNU1129

5'-Azido-2',5'-dideoxy-2'-fluorouridine

CAS: 1012080-88-4

5'-Azido-2',5'-dideoxy-2'-fluorouridine is a novel nucleoside that is a phosphoramidite. It is an antiviral agent that has been shown to inhibit the synthesis of RNA in cells. This drug also inhibits the growth of cancer cells and can be used for the treatment of leukemia, lymphoma, and myeloma. 5'-Azido-2',5'-dideoxy-2'-fluorouridine has been shown to bind to DNA through its azide group and form a stable covalent bond with the N7 position of guanine. This bond prevents the incorporation of adenosine triphosphate (ATP) into DNA, which prevents DNA transcription and replication.

Formula: C₉H₁₀FN₅O₄

Purity: Min. 95%

Molecular weight: 271.21 g/mol

Ref: 3D-NA163005