CAS 10121-91-2

Monodansylcadaverine

Description:

Monodansylcadaverine is a chemical compound characterized by its unique structure, which includes a cadaverine backbone modified with a dansyl group. This compound is often utilized in biochemical research, particularly in studies involving cellular processes and protein interactions. Monodansylcadaverine is known for its fluorescent properties, which make it a valuable tool in fluorescence microscopy and imaging techniques. The dansyl moiety provides a strong fluorescence signal, allowing researchers to track the compound's localization and dynamics within biological systems. Additionally, it can serve as a probe for studying polyamine metabolism and transport in cells. The compound is typically soluble in organic solvents and exhibits stability under standard laboratory conditions. However, like many chemical substances, it should be handled with care, following appropriate safety protocols to mitigate any potential hazards associated with its use. Overall, Monodansylcadaverine is an important reagent in the field of molecular biology and biochemistry, contributing to our understanding of cellular mechanisms.

Formula: C₁₇H₂₅N₃O₂S

InChI: InChI=1S/C17H25N3O2S/c1-20(2)16-10-6-9-15-14(16)8-7-11-17(15)23(21,22)19-13-5-3-4-12-18/h6-11,19H,3-5,12-13,18H2,1-2H3

InChI key: InChIKey=MLEBFEHOJICQQS-UHFFFAOYSA-N

SMILES: S(NCCCCCN)(=O)(=O)C=1C2=C(C(N(C)C)=CC=C2)C=CC1

Synonyms:

• 1-Naphthalenesulfonamide, N-(5-aminopentyl)-5-(dimethylamino)-
• Monodansylcadaverine
• Dansylcadaverine
• N-(5-Aminopentyl)-5-(dimethylamino)-1-naphthalenesulfonamide

1-Naphthalenesulfonamide, N-(5-aminopentyl)-5-(dimethylamino)-

CAS: 10121-91-2

Formula: C₁₇H₂₅N₃O₂S

Purity: 97%

Color and Shape: Solid

Molecular weight: 335.4643

Ref: IN-DA0003ZC

Dansylcadaverine

CAS: 10121-91-2

Dansylcadaverine

Purity: ≥98%

Molecular weight: 335.46g/mol

Ref: 54-BUP16201

Dansylcadaverine

CAS: 10121-91-2

Dansylcadaverine

Purity: 97%

Molecular weight: 335.46g/mol

Ref: 54-OR1025381

Dansylcadaverine

CAS: 10121-91-2

Formula: C₁₇H₂₅N₃O₂S

Purity: ≥ 97%

Color and Shape: White to yellow or green powder or solid

Molecular weight: 335.46

Ref: 7W-GW0087

Dansylcadaverine

CAS: 10121-91-2

Dansylcadaverine (Monodansyl cadaverine) is a fluorescent probe.

Formula: C₁₇H₂₅N₃O₂S

Purity: 98.33% - 99.6%

Color and Shape: Solid

Molecular weight: 335.46

Ref: TM-T18968

Dansylcadaverine

CAS: 10121-91-2

Dansylcadaverine is a fluorescent dye that binds to basic proteins in the cell. It has been shown to induce apoptosis in 3t3-l1 preadipocytes and can be used as a marker for apoptotic cells or as a marker of autophagy. The fluorescence intensity of dansylcadaverine increases when it binds to basic proteins on the surface of human pathogens, such as the surface glycoprotein on HIV-1. This binding has been shown to lead to induction of autophagy in macrophages, which may help clear these pathogens from the body and prevent disease progression. Dansylcadaverine also has physiological effects on mammalian cells, including an effect on epidermal growth factor receptor, which can be used for studying receptor-ligand interactions.

Formula: C₁₇H₂₅N₃O₂S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 335.46 g/mol

Ref: 3D-KAA12191

1-Naphthalenesulfonamide, N-(5-aminopentyl)-5-(dimethylamino)-

CAS: 10121-91-2

Purity: 98%

Molecular weight: 335.4700012

Ref: 10-F861492

Dansylcadaverine

Controlled Product

CAS: 10121-91-2

Applications Dansylcadaverine is a fluorescent amine probe, which is believed to directly inhibit vesicular transport. Studies indicate that Dansylcadaverine can act as a marker used to study autophagy in the cytoplasm and vacuoles of plants and mammalian cells.
References Munafó, D.B. and Colombo, M.I. 2001. J. Cell. Sci. 114: 3619-3629; Contento, A.L., et al. 2005. Plant J. 42: 598-608.

Formula: C₁₇H₂₅N₃O₂S

Color and Shape: Neat

Molecular weight: 335.46

Ref: TR-D181905