PX-866-17OH, identified by its CAS number 1012327-63-7, is a chemical compound that belongs to a class of molecules known for their potential therapeutic applications, particularly in the field of cancer research. This compound is a derivative of PX-866, which is an inhibitor of phosphoinositide 3-kinase (PI3K), a critical enzyme involved in various cellular processes, including growth, proliferation, and survival. The characteristics of PX-866-17OH include its ability to modulate signaling pathways that are often dysregulated in cancer cells, making it a subject of interest for developing targeted cancer therapies. The compound is typically characterized by its molecular structure, which includes specific functional groups that contribute to its biological activity. Additionally, its solubility, stability, and pharmacokinetic properties are essential for understanding its potential efficacy and safety in clinical settings. As research continues, further insights into its mechanism of action and therapeutic potential are anticipated.

PX-866-17OH is an active metabolite of PX-866 (Item No.
13645
).
1
It inhibits PI3Kα, PI3Kβ, PI3Kγ, and PI3Kδ (IC
50
s = 14, 57, 131, and 148 nM, respectively).

PX-866-17OH

1012327-63-7: PX-866-17OH, identified by its CAS number 1012327-63-7, is a chemical compound that belongs to a class of molecules known for their potential therapeutic applications, particularly in the field of cancer research. This compound is a derivative of PX-866, which is an inhibitor of phosphoinositide 3-kinase (PI3K), a critical enzyme involved in various cellular processes, including growth, proliferation, and survival. The characteristics of PX-866-17OH include its ability to modulate signaling pathways that are often dysregulated in cancer cells, making it a subject of interest for developing targeted cancer therapies. The compound is typically characterized by its molecular structure, which includes specific functional groups that contribute to its biological activity. Additionally, its solubility, stability, and pharmacokinetic properties are essential for understanding its potential efficacy and safety in clinical settings. As research continues, further insights into its mechanism of action and therapeutic potential are anticipated.

PX-866-17OH can be used in related research in the field of life sciences. Its product number is T36312 and CAS number is 1012327-63-7.

<p>PX-866-17OH is a research tool that can be used as an activator or ligand. It has been shown to bind to the receptor with high affinity and specificity. PX-866-17OH also binds to cells, which may be due to its ability to inhibit ion channels. In addition, PX-866-17OH has been shown to inhibit the activity of enzymes involved in protein synthesis and cell growth.</p>

CAS 1012327-63-7

PX-866-17OH

PX-866-17OH

Ref: TM-T36312

PX-866-17OH

Ref: 3D-MQB32763