CAS 101328-84-1

(S)-3(2h)-Pyridazinone, 6-(4-Aminophenyl)-4,5-Dihydro-5-Methyl-

Description:

(S)-3(2H)-Pyridazinone, 6-(4-Aminophenyl)-4,5-Dihydro-5-Methyl- is a chemical compound characterized by its pyridazinone core structure, which features a pyridazine ring with a ketone functional group. The presence of a 4-aminophenyl substituent indicates that there is an amino group attached to a phenyl ring, contributing to its potential biological activity. The compound also contains a dihydro structure, suggesting it has a saturated portion in its molecular framework, along with a methyl group that can influence its solubility and reactivity. This compound may exhibit various pharmacological properties, making it of interest in medicinal chemistry. Its specific stereochemistry, indicated by the (S) designation, suggests that it has a particular spatial arrangement that could affect its interaction with biological targets. Overall, this compound's unique structural features may contribute to its potential applications in drug development or other chemical research areas.

Formula: C₁₁H₁₃N₃O

(5S)-6-(4-Aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone

CAS: 101328-84-1

Formula: C₁₁H₁₃N₃O

Molecular weight: 203.2404

Ref: IN-DA00048H

Levosimendan Impurity 17

CAS: 101328-84-1

Formula: C₁₁H₁₃N₃O

Molecular weight: 203.25

Ref: 4Z-L-4219

(5S)-6-(4-Aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone

Controlled Product

CAS: 101328-84-1

Applications (5S)-6-(4-Aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone is an intermediate in the synthesis of Dextrosimendan (D299550), an isomer and impurity of Levosimendan (L378000), a bioactive enantiomer of Simendan (S466000). Levosimendan is a positive inotropic agent with vasodilating activity.
References Sandell, E.-P., et al.: J. Cardiovasc. Pharmacol., 26, S57 (1995); Pagel, P.S., et al.: Cardiovasc. Drug Rev., 14, 286 (1996)

Formula: C₁₁H₁₃N₃O

Color and Shape: Neat

Molecular weight: 203.24

Ref: TR-A622634