CAS 101343-69-5

Ocfentanil

Description:

Ocfentanil is a synthetic opioid analgesic that is structurally related to fentanyl, designed for use in pain management. It is characterized by its high potency, which is significantly greater than that of morphine, making it effective in treating severe pain, particularly in clinical settings. Ocfentanil acts primarily as a mu-opioid receptor agonist, leading to its analgesic effects. Its pharmacological profile includes rapid onset and a relatively short duration of action, which can be advantageous in certain medical applications. However, due to its potency, there is a significant risk of respiratory depression and overdose, necessitating careful dosing and monitoring. Ocfentanil is not widely used in clinical practice compared to other opioids, and its potential for abuse and dependence is a concern. As with other opioids, it is classified as a controlled substance in many jurisdictions, reflecting the need for regulation in its use and distribution. Overall, while ocfentanil has therapeutic potential, its safety profile requires stringent oversight.

Formula: C₂₂H₂₇FN₂O₂

InChI: InChI=1S/C22H27FN2O2/c1-27-17-22(26)25(21-10-6-5-9-20(21)23)19-12-15-24(16-13-19)14-11-18-7-3-2-4-8-18/h2-10,19H,11-17H2,1H3

InChI key: InChIKey=NYISTOZKVCMVEL-UHFFFAOYSA-N

SMILES: N(C(COC)=O)(C1=C(F)C=CC=C1)C2CCN(CCC3=CC=CC=C3)CC2

Synonyms:

• N-(2-Fluorophenyl)-2-methoxy-N-[1-(2-phenylethyl)-4-piperidinyl]acetamide
• Ocfentanil
• Acetamide, N-(2-fluorophenyl)-2-methoxy-N-[1-(2-phenylethyl)-4-piperidinyl]-

Ocfentanil

Controlled Product

CAS: 101343-69-5

Formula: C₂₂H₂₇FN₂O₂

Color and Shape: Neat

Molecular weight: 370.46

Ref: TR-O148400

Trideuteromethoxy Ocfentanyl Hydrochloride

Controlled Product

CAS: 101343-69-5

Formula: C₂₂H₂₄D₃FN₂O₂·HCl

Color and Shape: Neat

Molecular weight: 373.479

Ref: TR-O148402

Ocfentanil

Controlled Product

CAS: 101343-69-5

Ocfentanil is a potent opioid that is used as an analgesic. It has no significant binding to opioid receptors and instead acts as a competitive inhibitor of the peptide hormone, beta-endorphin. Ocfentanil binds to beta-endorphin with high affinity and prevents it from interacting with its receptor. It also inhibits the activation of these receptors by other agonists such as morphine. In addition, ocfentanil can bind to other peptides such as bradykinin and histamine via competitive inhibition. Ocfentanil may be used in research as a tool for identifying proteins involved in signal transduction pathways or ion channels.

Formula: C₂₂H₂₇FN₂O₂

Purity: Min. 95%

Molecular weight: 370.5 g/mol

Ref: 3D-BEA34369