CAS 10140-70-2

(-)-Curvularin

Description:

(-)-Curvularin is a naturally occurring compound classified as a polyketide, primarily produced by certain fungi, notably those in the genus Curvularia. It is characterized by its complex molecular structure, which includes multiple functional groups, contributing to its biological activity. The compound exhibits antifungal and antibacterial properties, making it of interest in pharmaceutical research. (-)-Curvularin has been studied for its potential applications in treating various infections and as a lead compound for developing new antimicrobial agents. Its stereochemistry is significant, as the specific configuration can influence its biological activity and interaction with target organisms. Additionally, (-)-Curvularin is soluble in organic solvents, which facilitates its extraction and purification from natural sources. The compound's unique properties and biological activities continue to be a subject of investigation in the fields of medicinal chemistry and natural product research.

Formula: C₁₆H₂₀O₅

InChI: InChI=1S/C16H20O5/c1-10-5-3-2-4-6-13(18)16-11(8-15(20)21-10)7-12(17)9-14(16)19/h7,9-10,17,19H,2-6,8H2,1H3/t10-/m0/s1

InChI key: InChIKey=VDUIGYAPSXCJFC-JTQLQIEISA-N

SMILES: OC1=C2C(=CC(O)=C1)CC(=O)O[C@@H](C)CCCCCC2=O

Synonyms:

• (-)-(S)-Curvularin
• (4R)-11,13-dihydroxy-4-methyl-4,5,6,7,8,9-hexahydro-2H-3-benzoxacyclododecine-2,10(1H)-dione
• (4S)-11,13-dihydroxy-4-methyl-4,5,6,7,8,9-hexahydro-2H-3-benzoxacyclododecine-2,10(1H)-dione
• (4S)-4,5,6,7,8,9-Hexahydro-11,13-dihydroxy-4-methyl-2H-3-benzoxacyclododecin-2,10(1H)-dione
• 11,13-dihydroxy-4-methyl-4,5,6,7,8,9-hexahydro-2H-3-benzoxacyclododecine-2,10(1H)-dione
• 2H-3-Benzoxacyclododecin-2,10(1H)-dione, 4,5,6,7,8,9-hexahydro-11,13-dihydroxy-4-methyl-
• 2H-3-Benzoxacyclododecin-2,10(1H)-dione, 4,5,6,7,8,9-hexahydro-11,13-dihydroxy-4-methyl-, (4S)-
• 2H-3-Benzoxacyclododecin-2,10(1H)-dione, 4,5,6,7,8,9-hexahydro-11,13-dihydroxy-4-methyl-, (S)-
• 2H-3-Benzoxacyclododecin-2,10(1H)-dione, 4,5,6,7,8,9-hexahydro-11,13-dihydroxy-4-methyl-, (S)- (9CI)
• Nsc 166071
• Curvularin

Curvularin

CAS: 10140-70-2

Formula: C₁₆H₂₀O₅

Purity: 100.0%

Color and Shape: Brownish powder

Molecular weight: 292.0

Ref: 8R-AD0067

2H-3-Benzoxacyclododecin-2,10(1H)-dione, 4,5,6,7,8,9-hexahydro-11,13-dihydroxy-4-methyl-, (4S)-

CAS: 10140-70-2

Formula: C₁₆H₂₀O₅

Purity: 98.0%

Color and Shape: Solid

Molecular weight: 292.3270

Ref: IN-DA0004ER

Curvularin

CAS: 10140-70-2

Curvularin

Molecular weight: 292.33g/mol

Ref: 54-BIBR1117

Curvularin

CAS: 10140-70-2

Curvularin ((S)-Curvularin) is a mycotoxin with anti-inflammatory activity and can be used to study inflammation.

Formula: C₁₆H₂₀O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 292.33

Ref: TM-T13628

Curvularin

CAS: 10140-70-2

Formula: C₁₆H₂₀O₅

Purity: ≥ 95%

Color and Shape: White to off-white powder

Molecular weight: 292.33

Ref: 7W-GA6429

Curvularin

CAS: 10140-70-2

Curvularin is a secondary metabolite, which is derived from the fungal genus *Curvularia*. This compound is produced through the natural biosynthetic pathways of filamentous fungi, specifically isolated from strains such as *Curvularia lunata*. Curvularin exerts its biological activity primarily through modulation of microtubule dynamics, making it a significant subject of study in cell biology. It disrupts the polymerization processes, impacting the assembly and stability of microtubules, which are critical components of the cytoskeleton involved in cell division, intracellular transport, and structural integrity.

Purity: Min. 95%

Ref: 3D-BC162716