CAS 101411-68-1

paulomycin A2

Description:

Paulomycin A2 is a natural product belonging to the class of polyketides, which are known for their diverse biological activities. It is derived from the fermentation of certain actinobacteria, particularly those in the genus Streptomyces. This compound exhibits notable antimicrobial properties, making it of interest in the field of medicinal chemistry and drug discovery. Structurally, paulomycin A2 features a complex arrangement of carbon, hydrogen, and oxygen atoms, contributing to its unique reactivity and biological function. The compound has been studied for its potential applications in treating various infections and may also exhibit cytotoxic effects against certain cancer cell lines. Its mechanism of action typically involves interference with cellular processes, although specific pathways may vary. As with many natural products, the extraction and purification of paulomycin A2 can be challenging, necessitating advanced techniques in organic chemistry. Overall, its intriguing properties continue to inspire research aimed at harnessing its therapeutic potential.

Formula: C₃₄H₄₆N₂O₁₇S

InChI: InChI=1/C34H46N2O17S/c1-8-14(3)31(43)50-16(5)34(46)15(4)49-22(10-21(34)47-7)52-27-25(39)29(33(45)11-19(38)24(35)23(28(33)40)30(41)42)51-20(12-48-17(6)37)26(27)53-32(44)18(9-2)36-13-54/h9,14-16,20-22,25-27,29,39,45-46H,8,10-12,35H2,1-7H3,(H,41,42)/b18-9-

Synonyms:

• 1-Cyclohexene-1-carboxylic acid, 5-[6-O-acetyl-3-O-[2,6-dideoxy-3-O-methyl-4-C-[(S)-1-(3-methyl-1-oxobutoxy)ethyl]-α-L-lyxo-hexopyranosyl]-4-O-[(Z)-2-isothiocyanato-1-oxo-2-buten-1-yl]-β-D-allopyranosyl]-2-amino-5-hydroxy-3,6-dioxo-, (5S)-
• paulomycin A2
• 6-O-acetyl-1-(4-amino-3-carboxy-1-hydroxy-2,5-dioxocyclohex-3-en-1-yl)-1,5-anhydro-3-O-(2,6-dideoxy-3-O-methyl-4-C-{1-[(2-methylbutanoyl)oxy]ethyl}hexopyranosyl)-4-O-[(2Z)-2-isothiocyanatobut-2-enoyl]hexitol
• 1-Cyclohexene-1-carboxylic acid, 5-(6-O-acetyl-3-O-(2,6-dideoxy-3-O-methyl-4-C-((S)-1-(3-methyl-1-oxobutoxy)ethyl)-alpha-L-lyxo-hexopyranosyl)-4-O-((Z)-2-isothiocyanato-1-oxo-2-butenyl)-beta-D-allopyranosyl)-2-amino-5-hydroxy-3,6-dioxo-, (S)-

Paulomycin A2

CAS: 101411-68-1

Paulomycin A2 exhibits antibacterial activity against Gram-positive bacteria and specifically inhibits Staphylococcus aureus that is resistant to penicillin, streptomycin, neomycin, and macrolide antibiotics.

Formula: C₃₄H₄₆N₂O₁₇S

Color and Shape: Solid

Molecular weight: 786.797

Ref: TM-TN10325