CAS 10149-21-0

DIETHYL 3-BROMOPROPYLMALONATE

Description:

Diethyl 3-bromopropylmalonate is an organic compound characterized by its structure, which includes a malonate moiety and a bromopropyl group. It is typically a colorless to pale yellow liquid or solid, depending on its purity and form. The compound features two ethyl ester groups attached to a central malonate structure, with a bromine atom substituting one of the hydrogen atoms on the propyl chain. This substitution imparts unique reactivity, making it useful in various synthetic applications, particularly in the synthesis of more complex organic molecules. Diethyl 3-bromopropylmalonate is often employed in the preparation of pharmaceuticals and agrochemicals due to its ability to undergo nucleophilic substitution reactions. It is soluble in organic solvents but has limited solubility in water. Safety data indicates that it should be handled with care, as it may pose health risks upon exposure. Proper storage in a cool, dry place away from light is recommended to maintain its stability and integrity.

Formula: C₁₀H₁₇BrO₄

Synonyms:

• Diethyl 2-(3-BroMopropyl)Malonate
• DIETHYL 3-BROMOPROPYLMALONATE
• 2-(3-BroMopropyl)propanedioic Acid 1,3-Diethyl Ester
• Propanedioic acid, 2-(3-bromopropyl)-, 1,3-diethyl ester

Propanedioic acid,2-(3-bromopropyl)-, 1,3-diethyl ester

CAS: 10149-21-0

Formula: C₁₀H₁₇BrO₄

Molecular weight: 281.1436

Ref: IN-DA0004LW

Diethyl 3-Bromopropylmalonate-D4

Controlled Product

CAS: 10149-21-0

Applications Diethyl 3-Bromopropylmalonate is a byproduct in the synthesis of Carboplatin-d4 (C177502), which is an analog of Cisplatin with reduced nephrotoxicity. Antineoplastic.
References Harland, S.J., et al.: Cancer Res., 44, 1693 (1984), Smith, I.E., et al.: Cancer Treat. Rep., 69, 43 (1985), Lygidakis, N.J., et al.: Interferon Cytokine Res., 15, 467 (1995),

Formula: C₁₀D₄H₁₃BrO₄

Color and Shape: Neat

Molecular weight: 285.168

Ref: TR-D443851