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CAS 101526-83-4

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Sematilide

Description:
Sematilide is a chemical compound primarily recognized for its role as an antiarrhythmic agent. It belongs to the class of drugs known as Class III antiarrhythmics, which are used to treat various types of cardiac arrhythmias by prolonging the cardiac action potential and refractory period. Sematilide functions by blocking potassium channels, thereby influencing the electrical activity of the heart. The compound is characterized by its specific molecular structure, which contributes to its pharmacological properties. It is typically administered in a controlled clinical setting due to its potential side effects, which may include cardiac toxicity and other systemic effects. As with many pharmaceutical agents, the therapeutic use of Sematilide requires careful monitoring of dosage and patient response to minimize adverse effects. Its development and use are guided by extensive research and clinical trials to ensure efficacy and safety in managing heart rhythm disorders.
Formula:C14H23N3O3S
InChI:InChI=1S/C14H23N3O3S/c1-4-17(5-2)11-10-15-14(18)12-6-8-13(9-7-12)16-21(3,19)20/h6-9,16H,4-5,10-11H2,1-3H3,(H,15,18)
InChI key:InChIKey=KHYPYQZQJSBPIX-UHFFFAOYSA-N
SMILES:C(NCCN(CC)CC)(=O)C1=CC=C(NS(C)(=O)=O)C=C1
Synonyms:
  • Benzamide, N-[2-(diethylamino)ethyl]-4-[(methylsulfonyl)amino]-
  • Ck 1752
  • N-[2-(diethylamino)ethyl]-4-[(methylsulfonyl)amino]benzamide
  • Sematilide [INN]
  • Sematilide
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