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CAS 101555-63-9

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D-Fmoc-pipecolic acid

Description:
D-Fmoc-pipecolic acid is a chemical compound characterized by its structure, which includes a pipecolic acid backbone modified with a 9-fluorenylmethoxycarbonyl (Fmoc) protecting group. This compound is often utilized in peptide synthesis as a protected amino acid, allowing for the selective formation of peptide bonds while preventing unwanted reactions at the amino group. The Fmoc group is known for its stability under basic conditions and can be removed under mild acidic conditions, making it a popular choice in solid-phase peptide synthesis. D-Fmoc-pipecolic acid is a chiral molecule, with the "D" designation indicating the specific stereochemistry of the pipecolic acid moiety. Its unique properties, including solubility in organic solvents and its role in facilitating the synthesis of cyclic peptides, make it valuable in pharmaceutical research and development. Additionally, the compound's CAS number, 101555-63-9, serves as a unique identifier for regulatory and safety information.
Formula:C21H21NO4
InChI:InChI=1/C21H21NO4/c23-20(24)19-11-5-6-12-22(19)21(25)26-13-18-16-9-3-1-7-14(16)15-8-2-4-10-17(15)18/h1-4,7-10,18-19H,5-6,11-13H2,(H,23,24)/t19-/m1/s1
InChI key:InChIKey=CKLAZLINARHOTG-LJQANCHMSA-N
SMILES:C(OC(=O)N1[C@@H](C(O)=O)CCCC1)C2C=3C(C=4C2=CC=CC4)=CC=CC3
Synonyms:
  • (2R)-1-[(9H-Fluoren-9-ylmethoxy)carbonyl]hexahydropyridine-2-carboxylic acid
  • (2R)-1-[(9H-fluoren-9-ylmethoxy)carbonyl]piperidine-2-carboxylic acid
  • (2R)-1-[[(9H-Fluoren-9-yl)methoxy]carbonyl]piperidine-2-carboxylic acid
  • (2S)-1-[(9H-fluoren-9-ylmethoxy)carbonyl]piperidine-2-carboxylic acid
  • (R)-N-(9-fluorenylmethyloxycarbonyl)-piperidine-2-carboxylic acid
  • (R)-N-Fmoc-piperidine-2-carboxylic acid
  • 1,2-Piperidinedicarboxylic acid, 1-(9H-fluoren-9-ylmethyl) ester, (2R)-
  • 1,2-Piperidinedicarboxylic acid, 1-(9H-fluoren-9-ylmethyl) ester, (R)-
  • 1-Fmoc-piperidine-2-carboxylic acid
  • 1-[(9H-fluoren-9-ylmethoxy)carbonyl]piperidine-2-carboxylic acid
  • See more synonyms
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