CAS 1015856-57-1

1-(Ethyl-1,1,2,2,2-d5)-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid

Description:

1-(Ethyl-1,1,2,2,2-d5)-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid is a synthetic compound characterized by its complex structure, which includes a quinoline core, a piperazine moiety, and a fluorine substituent. The presence of the ethyl group, specifically deuterated at five positions, indicates its use in studies requiring isotopic labeling, such as pharmacokinetic or metabolic investigations. This compound exhibits properties typical of quinolone derivatives, including potential antibacterial or antiviral activity, owing to its ability to interfere with bacterial DNA synthesis. The carboxylic acid functional group contributes to its solubility in polar solvents and may influence its biological activity and interaction with target proteins. Additionally, the fluorine atom can enhance lipophilicity and metabolic stability. Overall, this compound's unique structural features suggest it may have applications in medicinal chemistry, particularly in the development of new therapeutic agents.

Formula: C₁₆H₁₃D₅FN₃O₃

InChI: InChI=1S/C16H18FN3O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20/h7-9,18H,2-6H2,1H3,(H,22,23)/i1D3,2D2

InChI key: InChIKey=OGJPXUAPXNRGGI-ZBJDZAJPSA-N

SMILES: C(C([2H])([2H])[2H])(N1C=2C(C(=O)C(C(O)=O)=C1)=CC(F)=C(C2)N3CCNCC3)([2H])[2H]

Synonyms:

• 1-(Ethyl-1,1,2,2,2-d5)-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
• Norfloxacin-d5
• 3-Quinolinecarboxylic acid, 1-(ethyl-1,1,2,2,2-d5)-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-

Norfloxacin-d5

CAS: 1015856-57-1

Formula: C₁₆H₁₃D₅FN₃O₃

Color and Shape: White To Off-White Solid

Molecular weight: 324.37

Ref: 4Z-N-3218

Norfloxacin-d5 (ethyl-d5)

CAS: 1015856-57-1

Purity: 99 atom % D

Color and Shape: White To Yellow Solid

Molecular weight: 324.37

Ref: 3U-D7196

Norfloxacin D5 100 µg/mL in Acetonitrile

Controlled Product

CAS: 1015856-57-1

Formula: C₁₆H₅H₁₃FN₃O₃

Color and Shape: Single Solution

Molecular weight: 324.36

Ref: 04-A15648010AL-100

Norfloxacin D5

Controlled Product

CAS: 1015856-57-1

Formula: C₁₆H₅H₁₃FN₃O₃

Color and Shape: Neat

Molecular weight: 324.36

Ref: 04-C15648010

Norfloxacin-d5

Controlled Product

CAS: 1015856-57-1

Applications Norfloxacin-d5 is deuterium labeled Norfloxacin (N681000), a synthetic fluoroquinolone and an antibacterial agent. Norfloxacin can be used to treat urinary tract infections.
References Koga, H., et al.: J. Med. Chem., 23, 1358 (1980), Hirai, K., et al.: Antimicrob. Agents Chemother., 19, 188 (1981), Holmes, B., et al.: Drugs, 30, 482 (1985),

Formula: C₁₆₂H₅H₁₃FN₃O₃

Color and Shape: Neat

Molecular weight: 324.36

Ref: TR-N681003

3-Quinolinecarboxylic acid, 1-(ethyl-1,1,2,2,2-d5)-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-

CAS: 1015856-57-1

Formula: C₁₆H₁₃D₅FN₃O₃

Purity: 99.0%

Color and Shape: Solid

Molecular weight: 324.3616

Ref: IN-DA0004WB