CAS 1018899-04-1: Sotagliflozin

Description: Sotagliflozin is a medication primarily used in the management of type 1 and type 2 diabetes mellitus. It functions as a dual inhibitor of sodium-glucose co-transporter 1 (SGLT1) and sodium-glucose co-transporter 2 (SGLT2), which are proteins involved in glucose reabsorption in the kidneys and intestines. By inhibiting these transporters, sotagliflozin promotes the excretion of glucose through urine and reduces glucose absorption in the gastrointestinal tract, thereby helping to lower blood sugar levels. The compound is characterized by its chemical structure, which includes specific functional groups that contribute to its pharmacological activity. Sotagliflozin is typically administered orally and may be used in conjunction with other antidiabetic medications. Its safety profile includes potential side effects such as urinary tract infections and dehydration, which are common with SGLT2 inhibitors. Overall, sotagliflozin represents a novel approach to diabetes management, targeting multiple pathways to improve glycemic control.

Formula: C₂₁H₂₅ClO₅S

InChI: InChI=1S/C21H25ClO5S/c1-3-26-15-7-4-12(5-8-15)10-14-11-13(6-9-16(14)22)20-18(24)17(23)19(25)21(27-20)28-2/h4-9,11,17-21,23-25H,3,10H2,1-2H3/t17-,18-,19+,20+,21-/m1/s1

InChI key: InChIKey=QKDRXGFQVGOQKS-CRSSMBPESA-N

SMILES: ClC1=CC=C(C=C1CC2=CC=C(OCC)C=C2)C3OC(SC)C(O)C(O)C3O

Synonyms:

• (5S)-Methyl 5-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-1-thio-β-<span class="text-smallcaps">L</span>-xylopyranoside
• Lp 802034
• Lx-4211
• Sotagliflozin
• Zynquista
• β-<span class="text-smallcaps">L</span>-Xylopyranoside, methyl 5-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-1-thio-, (5S)-
• β-L-Xylopyranoside, methyl 5-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-1-thio-, (5S)-
• (5S)-Methyl 5-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-1-thio-β-L-xylopyranoside

β-L-Xylopyranoside, methyl 5-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-1-thio-, (5S)-

CAS: 1018899-04-1

• Formula: C₂₁H₂₅ClO₅S
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 424.9382

(2S,3R,4R,5S,6R)-2-[4-Chloro-3-[(4-Ethoxyphenyl)Methyl]Phenyl]-6-Methylsulfanyloxane-3,4,5-Triol

CAS: 1018899-04-1

• Purity: 98%
• Molecular weight: 424.94g/mol

Sotagliflozin

CAS: 1018899-04-1

Sotagliflozin (LP-802034) is an orally bioavailable inhibitor of the sodium-glucose co-transporter subtype 1 (SGLT1) and …

• Formula: C₂₁H₂₅ClO₅S
• Purity: 99% - 99.73%
• Color and Shape: Solid
• Molecular weight: 424.94

LX4211

CAS: 1018899-04-1

Inhibitor of sodium-glucose cotransporters SGLT1 and SGLT2

• Formula: C₂₁H₂₅ClO₅S
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 424.94 g/mol

Sotagliflozin

CAS: 1018899-04-1

• Formula: C₂₁H₂₅ClO₅S
• Color and Shape: Neat
• Molecular weight: 424.938