CAS 1019206-88-2: Regorafenib hydrate

Description: Regorafenib hydrate is a small-molecule tyrosine kinase inhibitor primarily used in the treatment of various cancers, including colorectal cancer and gastrointestinal stromal tumors. It functions by inhibiting multiple kinases involved in tumor growth and angiogenesis, thereby disrupting the signaling pathways that promote cancer progression. The substance is characterized by its complex structure, which includes a pyridine ring and a phenyl group, contributing to its pharmacological activity. Regorafenib hydrate is typically administered orally and is known for its moderate solubility in water, which is enhanced in its hydrate form. The hydrate form is significant as it can influence the drug's stability, solubility, and bioavailability. Common side effects associated with regorafenib include fatigue, diarrhea, and hypertension, reflecting its systemic effects on both cancer cells and normal tissues. As with many targeted therapies, careful monitoring is essential to manage potential adverse effects and ensure optimal therapeutic outcomes.

Synonyms:

• Regorafenib monohydrate

Regorafenib monohydrate CRS

CAS: 1019206-88-2

• Color and Shape: Powder

Regorafenib

CAS: 1019206-88-2

Compounds containing an unfused pyridine ring in the structure, nesoi

• Formula: C₂₁H₁₅ClF₄N₄O₃·H₂O
• Color and Shape: White Brown Powder
• Molecular weight: 500.08745

4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide hydrate

CAS: 1019206-88-2

• Formula: C₂₁H₁₇ClF₄N₄O₄
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 500.83069279999984

Regorafenib (Monohydrate)

CAS: 1019206-88-2

• Purity: 98%
• Molecular weight: 500.83g/mol

Regorafenib monohydrate

CAS: 1019206-88-2

• Purity: 99.69%
• Molecular weight: 500.83g/mol

Regorafenib Monohydrate

CAS: 1019206-88-2

• Formula: C₂₁H₁₅ClF₄N₄O₃·H₂O
• Color and Shape: Neat
• Molecular weight: 500.8307

Regorafenib monohydrate

CAS: 1019206-88-2

Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, …

• Formula: C₂₁H₁₇ClF₄N₄O₄
• Purity: 99.69%
• Color and Shape: Solid
• Molecular weight: 500.83

Regorafenib monohydrate

CAS: 1019206-88-2

• Purity: 98%
• Molecular weight: 500.829986572266

Regorafenib monohydrate

CAS: 1019206-88-2

Multi-kinase inhibitor; inhibits epoxide hydrolase; antineoplastic

• Formula: C₂₁H₁₅ClF₄N₄O₃•H₂O
• Purity: Min. 95%
• Molecular weight: 500.83 g/mol