CAS 1019453-85-0

2-[(2,4-Dimethylphenyl)sulfanyl]aniline

Description:

2-[(2,4-Dimethylphenyl)sulfanyl]aniline, identified by its CAS number 1019453-85-0, is an organic compound that features a sulfenyl group attached to an aniline structure. This compound consists of a benzene ring substituted with both a sulfanyl group (-S-) and an aniline group (-NH2), which contributes to its chemical reactivity and potential applications in various fields, including pharmaceuticals and materials science. The presence of the dimethylphenyl group enhances its hydrophobic characteristics, influencing its solubility and interaction with other substances. The compound may exhibit properties such as moderate to high melting and boiling points, depending on its molecular interactions. Additionally, the presence of the amino group can facilitate hydrogen bonding, affecting its reactivity and potential as a ligand in coordination chemistry. Overall, 2-[(2,4-Dimethylphenyl)sulfanyl]aniline is a versatile compound with potential applications in organic synthesis and as an intermediate in the production of more complex chemical entities.

Formula: C₁₄H₁₅NS

Synonyms:

• 2-[(2,4-Dimethylphenyl)thio]benzenamine
• 2-(2,4-Dimethylphenylthio)Benzeneamine
• Wortioxetine intermediate: 2-((2,4-dimethylphenyl) thio) aniline
• 2-((2,4-DiMethylphenyl)thio)phenylaMine
• Vortioxetine Impurity 60
• VOR-IM B
• Benzenamine, 2-[(2,4-dimethylphenyl)thio]-
• 2-((2,4-dimethylphenyl)thio)aniline
• VOR-IM D

Benzenamine, 2-[(2,4-dimethylphenyl)thio]-

CAS: 1019453-85-0

Formula: C₁₄H₁₅NS

Purity: 97%

Color and Shape: Liquid

Molecular weight: 229.3406

Ref: IN-DA00060Y

Vortioxetine Impurity 33

CAS: 1019453-85-0

Formula: C₁₄H₁₅NS

Color and Shape: Yellow Solid

Molecular weight: 229.34

Ref: 4Z-V-043036

2-((2,4-Dimethylphenyl)thio)aniline

CAS: 1019453-85-0

2-((2,4-Dimethylphenyl)thio)aniline

Purity: 97%

Ref: 54-OR1038105

2-[(2,4-Dimethylphenyl)sulfanyl]aniline

Controlled Product

CAS: 1019453-85-0

Stability Hygroscopic
Applications 2-[(2,4-Dimethylphenyl)sulfanyl]aniline is used in the study of N-O-glucuronide metabolites of Lu AA21004 (Vortioxetine [V766000]), an antidepressant.
References Bang-Andersen, B., et al.: J. Med. Chem., 54, 3206 (2011); Mørk, A., et al.: J. Pharmacol. Exp. Ther., 340, 666 (2012); Mørk, A., et al.: Pharmacol. Biochem. Behav. 105C, 41 (2013); Uldam, H. et al.: Drug Metab. Disp., 39, 2264 (2011);

Formula: C₁₄H₁₅NS

Color and Shape: Light Brown To Dark Brown

Molecular weight: 229.34

Ref: TR-D447335

2-((2,4-Dimethylphenyl)thio)aniline

CAS: 1019453-85-0

Purity: 97%

Molecular weight: 229.3399963

Ref: 10-F694970

Vortioxetine Impurity 33

CAS: 1019453-85-0

Formula: C₁₄H₁₅NS

Molecular weight: 229.34

Ref: ST-EA-CP-V36010

2-[(2,4-Dimethylphenyl)sulfanyl]aniline

CAS: 1019453-85-0

2-[(2,4-Dimethylphenyl)sulfanyl]aniline is a synthetic drug substance that inhibits the growth of Mycobacterium tuberculosis. It has been shown to be effective in inhibiting the replication of DNA and RNA, which is essential for bacterial growth. 2-[(2,4-Dimethylphenyl)sulfanyl]aniline also has genotoxic impurities, so it should be handled with caution. This active compound is used as a starting material in the synthesis of other antituberculous agents such as ethionamide, pyridoxine, and piperazine. The synthesis of this compound can be achieved by reacting ammonium formate with 2-(p-aminophenyl) sulfanilide.

Formula: C₁₄H₁₅NS

Purity: Min. 95%

Molecular weight: 229.34 g/mol

Ref: 3D-FD157099