CAS 101975-10-4

Zardaverine

Description:

Zardaverine, with the CAS number 101975-10-4, is a chemical compound that has been studied primarily for its potential therapeutic applications. It is classified as a selective phosphodiesterase (PDE) inhibitor, specifically targeting PDE4, which plays a crucial role in the regulation of intracellular signaling pathways involving cyclic adenosine monophosphate (cAMP). By inhibiting this enzyme, Zardaverine can enhance cAMP levels, leading to various physiological effects, including anti-inflammatory and bronchodilator activities. This makes it of interest in the treatment of respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). Zardaverine is also noted for its ability to modulate smooth muscle relaxation and has been investigated for its potential in cardiovascular applications. Its chemical structure features a unique arrangement of functional groups that contribute to its biological activity. As with many pharmacological agents, the safety profile, pharmacokinetics, and specific therapeutic uses are subjects of ongoing research to fully understand its efficacy and potential side effects.

Formula: C₁₂H₁₀F₂N₂O₃

InChI: InChI=1S/C12H10F2N2O3/c1-18-10-6-7(2-4-9(10)19-12(13)14)8-3-5-11(17)16-15-8/h2-6,12H,1H3,(H,16,17)

InChI key: InChIKey=HJMQDJPMQIHLPB-UHFFFAOYSA-N

SMILES: O(C)C=1C=C(C=CC1OC(F)F)C=2C=CC(=O)NN2

Synonyms:

• 3(2H)-Pyridazinone, 6-[4-(difluoromethoxy)-3-methoxyphenyl]-
• 6-(4-(Difluoromethoxy)-3-methoxyphenyl)-3(2H)-pyridazinone
• 6-[4-(difluoromethoxy)-3-methoxyphenyl]pyridazin-3(2H)-one
• Unii-Tq358Gwh6Y
• Zardaverina
• Zardaverina [INN-Spanish]
• Zardaverine [INN]
• Zardaverinum
• Zardaverinum [INN-Latin]
• Zardaverine

3(2H)-Pyridazinone, 6-[4-(difluoromethoxy)-3-methoxyphenyl]-

CAS: 101975-10-4

Formula: C₁₂H₁₀F₂N₂O₃

Purity: 98%

Molecular weight: 268.2162

Ref: IN-DA00064I

6-(4-(Difluoromethoxy)-3-methoxyphenyl)pyridazin-3(2H)-one

CAS: 101975-10-4

6-(4-(Difluoromethoxy)-3-methoxyphenyl)pyridazin-3(2H)-one

Purity: 98%

Molecular weight: 268.22g/mol

Ref: 54-PC1007956

Zardaverine phosphodiesterase inhibitor

CAS: 101975-10-4

Formula: C₁₂H₁₀F₂N₂O₃

Molecular weight: 268.22

Ref: 7W-GK6365

Zardaverine

CAS: 101975-10-4

Zardaverine (BY 290) is a PDE3/4 inhibitor with anti-hepatocarcinogenic activity and is used in the study of acute renal failure and chronic airflow obstruction

Formula: C₁₂H₁₀F₂N₂O₃

Purity: 99.11%

Color and Shape: Solid

Molecular weight: 268.22

Ref: TM-T17284

Zardaverine

Controlled Product

CAS: 101975-10-4

Formula: C₁₂H₁₀F₂N₂O₃

Color and Shape: Neat

Molecular weight: 268.216

Ref: TR-Z150600

Zardaverine

CAS: 101975-10-4

Inhibitor of phosphodiesterase isoenzymes PDE3 and PDE4

Formula: C₁₂H₁₀F₂N₃O₃

Purity: Min. 95%

Molecular weight: 282.22 g/mol

Ref: 3D-BZ161227