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CAS 1020172-07-9

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Rebastinib

Description:
Rebastinib is a small molecule inhibitor primarily known for its role in targeting specific kinases involved in cancer cell signaling pathways. It is particularly noted for its activity against the ABL and SRC family of kinases, which are implicated in various malignancies, including chronic myeloid leukemia and solid tumors. The compound is characterized by its ability to disrupt the phosphorylation processes that drive tumor growth and survival, making it a candidate for therapeutic applications in oncology. Rebastinib has been studied in clinical trials, showcasing its potential to inhibit tumor progression and improve patient outcomes. Its chemical structure includes specific functional groups that contribute to its binding affinity and selectivity for its targets. As with many investigational drugs, ongoing research is focused on optimizing its efficacy, understanding its pharmacokinetics, and evaluating its safety profile in diverse patient populations. Overall, Rebastinib represents a promising avenue in targeted cancer therapy, reflecting the broader trend of developing precision medicines in oncology.
Formula:C30H28FN7O3
Synonyms:
  • N-[3-tert-Butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl]-N'-[2-fluoro-4-[(2-(methylcarbamoyl)pyridin-4-yl)oxy]phenyl]urea
  • Dcc-2036
  • N-[3-tert-Butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl]-N'-[2-fluoro-4-[(2-(MethylcarbaMoyl)pyridin-4-yl)
  • N-[3-tert-Butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl]-N'-[2-fluoro-4-[(2-(methylcarbamoyl)pyridin-4-yl)oxy]phenyl]urea DCC-2036 (Rebastinib)
  • 2-Pyridinecarboxamide, 4-[4-[[[[3-(1,1-dimethylethyl)-1-(6-quinolinyl)-1H-pyrazol-5-yl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-
  • DCC-2036 (Rebastinib)
  • Rebastinib(DCC-2036)
  • Rebastinib Tosylate
  • DCC2036;DCC 2036
  • 1-(3-tert-butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl)-3-(2-fluoro-4-(2-(methylcarbamoyl)pyridin-4-yloxy)phenyl)urea
  • See more synonyms
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Found 5 products.