CAS 1020315-31-4

Pf 04457845

Description:

Pf 04457845, identified by its CAS number 1020315-31-4, is a chemical compound that has garnered attention in pharmaceutical research, particularly for its potential therapeutic applications. It is characterized as a selective inhibitor of certain enzymes, which may play a role in various biological pathways. The compound's structure typically includes specific functional groups that contribute to its biological activity and selectivity. In terms of solubility, it may exhibit moderate to high solubility in organic solvents, while its solubility in water can vary based on its molecular structure. The compound's stability is influenced by environmental factors such as pH and temperature, which are critical for its storage and handling. Additionally, Pf 04457845 may undergo metabolic transformations in biological systems, impacting its pharmacokinetics and efficacy. Overall, its characteristics make it a subject of interest in drug discovery and development, particularly in the context of targeting specific diseases or conditions.

Formula: C₂₃H₂₀F₃N₅O₂

InChI: InChI=1S/C23H20F3N5O2/c24-23(25,26)18-6-7-21(27-15-18)33-19-4-1-3-17(14-19)13-16-8-11-31(12-9-16)22(32)29-20-5-2-10-28-30-20/h1-7,10,13-15H,8-9,11-12H2,(H,29,30,32)

InChI key: InChIKey=BATCTBJIJJEPHM-UHFFFAOYSA-N

SMILES: C(NC1=CC=CN=N1)(=O)N2CCC(=CC3=CC(OC4=CC=C(C(F)(F)F)C=N4)=CC=C3)CC2

Redafamdastat

CAS: 1020315-31-4

Formula: C₂₃H₂₀F₃N₅O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 455.4324

Ref: IN-DA0006EM

PF-04457845

CAS: 1020315-31-4

PF-04457845

Purity: ≥98%

Molecular weight: 455.43g/mol

Ref: 54-BUP09922

PF-04457845

CAS: 1020315-31-4

PF-04457845 is a greatly and effctive FAAH inhibitor, and for hFAAH(IC50=7.2±0.63 nM) and rFAAH(IC50=7.4±0.62 nM).

Formula: C₂₃H₂₀F₃N₅O₂

Purity: >99.99%

Color and Shape: Solid

Molecular weight: 455.43

Ref: TM-T4323

PF-04457845

CAS: 1020315-31-4

PF-04457845 is a nonsteroidal anti-inflammatory drug that binds to the endocannabinoid receptor and inhibits the release of growth factor. It is used to treat cancer, pain, and other conditions in which inflammation or growth factors are implicated. PF-04457845 has been shown to be an effective treatment for chronic pain and cancer-related symptoms in animal models. This drug has pharmacological properties that inhibit the production of proinflammatory cytokines and nitric oxide synthase, which are important in the development of cancer. The pharmacokinetics of PF-04457845 have also been studied in positron emission tomography (PET) imaging studies with [11C]PF-04457845.

Formula: C₂₃H₂₀F₃N₅O₂

Purity: Min. 95%

Molecular weight: 455.43 g/mol

Ref: 3D-FP103118