CAS 1020657-43-5

N,O3'-dibenzoylgeMcitabine

Description:

N,O3'-dibenzoylgeMcitabine, identified by its CAS number 1020657-43-5, is a chemical compound that belongs to the class of nucleoside analogs. It is characterized by the presence of a modified nucleoside structure, which typically includes a ribose sugar moiety linked to a nitrogenous base, along with two benzoyl groups attached to the nitrogen and oxygen positions. This modification can enhance the compound's stability and bioavailability, making it of interest in pharmaceutical applications, particularly in antiviral or anticancer therapies. The compound's molecular structure contributes to its potential interactions with biological targets, influencing its pharmacokinetics and pharmacodynamics. Additionally, its synthesis and characterization involve standard organic chemistry techniques, including purification methods such as chromatography. As with many nucleoside analogs, the biological activity of N,O3'-dibenzoylgeMcitabine is likely to be assessed through in vitro and in vivo studies to determine its efficacy and safety profile.

Formula: C₂₃H₁₉F₂N₃O₆

Synonyms:

• N4,O-3'-Dibenzoyl-2',2'-difluoro-2-deoxycytidine
• N-Benzoyl-2'-deoxy-2',2'-difluorocytidine 3'-Benzoate
• Cytidine, N-benzoyl-2'-deoxy-2',2'-difluoro-, 3'-benzoate
• N,O3'-dibenzoylgeMcitabine

N-​Benzoyl-​2'-​deoxy-​2',​2'-​difluorocytidine 3’-Benzoate

Controlled Product

CAS: 1020657-43-5

Applications N-Benzoyl-2'-deoxy-2',2'-difluorocytidine 3’-Benzoate is an intermediate in the synthesis of Gemcitabine (G305000) metabolites.
References Baraniak, J., et al.: Bioorg. Med. Chem., 22, 2133 (2014); Labrioli, M.A., et al.: Bioorg. Med. Chem., 22, 2303 (2014);

Formula: C₂₃H₁₉F₂N₃O₆

Color and Shape: Neat

Molecular weight: 471.41

Ref: TR-B207915

N-​Benzoyl-​2'-​deoxy-​2',​2'-​difluorocytidine 3’-benzoate

CAS: 1020657-43-5

Formula: C₂₃H₁₉F₂N₃O₆

Molecular weight: 471.42

Ref: ST-EA-CP-G7035