CAS 1020719-34-9

8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine-2,3,4,5,5-d5

Description:

8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine-2,3,4,5,5-d5 is a complex organic compound characterized by its unique bicyclic structure, which incorporates both a benzo and a cycloheptane moiety. The presence of a chlorine atom and a piperidinylidene group contributes to its reactivity and potential biological activity. The deuterated form indicated by "d5" suggests that five hydrogen atoms in the molecule are replaced with deuterium, which can influence the compound's stability, solubility, and isotopic labeling in research applications. This compound may exhibit specific pharmacological properties, making it of interest in medicinal chemistry. Its structural features suggest potential interactions with biological targets, which could be explored in drug development. However, detailed studies on its pharmacodynamics, pharmacokinetics, and toxicity would be necessary to fully understand its characteristics and applications.

Formula: C₁₉H₁₄ClD₅N₂

InChI: InChI=1S/C19H19ClN2/c20-16-5-6-17-15(12-16)4-3-14-2-1-9-22-19(14)18(17)13-7-10-21-11-8-13/h1-2,5-6,9,12,21H,3-4,7-8,10-11H2/i1D,2D,3D2,9D

InChI key: InChIKey=JAUOIFJMECXRGI-ZMXCGMLLSA-N

SMILES: ClC=1C=C2C(C(C=3C(C(C2)([2H])[2H])=C(C(=C(N3)[2H])[2H])[2H])=C4CCNCC4)=CC1

Synonyms:

• 5H-Benzo[5,6]cyclohepta[1,2-b]pyridine-2,3,4,5,5-d5, 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-
• 8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine-2,3,4,5,5-d5

Desloratadine-d5

CAS: 1020719-34-9

Formula: C₁₉H₁₄D₅ClN₂

Color and Shape: Pink To Off-White Solid

Molecular weight: 315.86

Ref: 4Z-L-104

Desloratadine-d5

CAS: 1020719-34-9

Desloratadine-d5 is an analog of the antihistamine drug Desloratadine, which has been shown to have potential anticancer properties. This compound has been found to induce apoptosis in cancer cells by inhibiting cyclin-dependent kinases (CDKs) that are involved in cell cycle progression. Desloratadine-d5 has been tested on human and Chinese hamster ovary cell lines, demonstrating its ability to inhibit tumor growth. This compound can be detected in urine and can serve as a biomarker for the assessment of CDK inhibitors for cancer treatment. Desloratadine-d5 may prove to be a promising inhibitor for kinase-targeted anticancer therapies.

Formula: C₁₉H₁₉ClN₂

Purity: Min. 95%

Molecular weight: 315.8 g/mol

Ref: 3D-VQB71934