CAS 1020719-55-4

RAC 9-HYDROXYRISPERIDONE-D4

Description:

RAC 9-Hydroxyrisperidone-D4 is a deuterated analog of 9-hydroxyrisperidone, which is a metabolite of the antipsychotic medication risperidone. The deuteration (indicated by the "D4" in its name) involves the substitution of hydrogen atoms with deuterium, a stable isotope of hydrogen, which can enhance the compound's stability and alter its pharmacokinetic properties. This compound is primarily used in research settings, particularly in pharmacokinetic studies and metabolic profiling, to trace the behavior of risperidone in biological systems. Its chemical structure includes a piperidine ring and a benzisoxazole moiety, characteristic of many antipsychotic agents. The presence of deuterium allows for improved detection and quantification in analytical techniques such as mass spectrometry. As with other substances in its class, it may exhibit interactions with various neurotransmitter receptors, contributing to its pharmacological effects. However, specific biological activity and safety profiles would depend on the context of its use and require further investigation.

Formula: C₂₃H₂₇FN₄O₃

Synonyms:

• 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl-d4]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
• RO 76477-d4
• ]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
• 4
• rac 9-Hydroxy Risperidone-d4See P141002
• R 76477-d4
• 9-Hydroxyrisperidone-D4 solution
• Paliperidone-d4 (Major)
• 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl- 4H-pyrido[1,2-α]pyrimidin-4-one-d4
• Paliperidone-d4
• 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl-1,1,2,2-d
• 9-Hydroxy Risperidone-d4 (Paliperidone-d4)

Risperidone EP Impurity C-d4 (9-Hydroxy Risperidone-d4, Paliperidone-d4)

CAS: 1020719-55-4

Formula: C₂₃H₂₃D₄FN₄O₃

Color and Shape: Pale Yellow Solid

Molecular weight: 430.52

Ref: 4Z-R-064

Paliperidone-d4 (Major)

Controlled Product

CAS: 1020719-55-4

Applications A deuterated analog of Paliperidone, a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Tiberghien, F., et al.: Anticancer Drugs, 7, 568 (1996), Kansy, M., et al.: J. Med. Chem., 41, 1007 (1998), Kerns, E., et al.: J. Pharm. Sci., 90, 1838 (2001), Kerr, K., et al.: J. Biol. Chem., 276, 8657 (2001), Doran, A., et al.: Drug Metab. Dispos., 33, 165 (2005),

Formula: C₂₃₂H₄H₂₃FN₄O₃

Color and Shape: Neat

Molecular weight: 430.51

Ref: TR-P141003

Paliperidone-d4

Controlled Product

CAS: 1020719-55-4

Applications A deuterated analog of Paliperidone, a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Tiberghien, F., et al.: Anticancer Drugs, 7, 568 (1996), Kansy, M., et al.: J. Med. Chem., 41, 1007 (1998), Kerns, E., et al.: J. Pharm. Sci., 90, 1838 (2001), Kerr, K., et al.: J. Biol. Chem., 276, 8657 (2001), Doran, A., et al.: Drug Metab. Dispos., 33, 165 (2005),

Formula: C₂₃₂H₄H₂₃FN₄O₃

Color and Shape: Beige

Molecular weight: 430.51

Ref: TR-P141002

4H-Pyrido[1,2-a]pyrimidin-4-one, 3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl-1,1,2,2-d4]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-

CAS: 1020719-55-4

Formula: C₂₃H₂₃D₄FN₄O₃

Purity: %

Color and Shape: Solid

Molecular weight: 430.5085

Ref: IN-DA0006J9