CAS 10212-19-8

2'-Chloro-2'-deoxycytidine

Description:

2'-Chloro-2'-deoxycytidine, commonly referred to as cladribine, is a synthetic nucleoside analog of deoxycytidine. It features a chlorine atom at the 2' position of the ribose sugar, which distinguishes it from natural nucleosides. This modification enhances its stability and alters its biological activity. Cladribine is primarily used in the treatment of certain hematological malignancies, such as hairy cell leukemia and multiple sclerosis, due to its ability to interfere with DNA synthesis and repair. The compound exhibits antimetabolite properties, leading to the inhibition of cell proliferation, particularly in rapidly dividing cells. In terms of solubility, cladribine is typically soluble in water and exhibits moderate stability under physiological conditions. Its mechanism of action involves incorporation into DNA, resulting in the disruption of normal cellular processes. As a pharmaceutical agent, cladribine is administered via injection, and its pharmacokinetics and dosing regimens are carefully managed to optimize therapeutic outcomes while minimizing potential side effects.

Formula: C₉H₁₂ClN₃O₄

InChI: InChI=1/C9H12ClN3O4/c10-6-7(15)4(3-14)17-8(6)13-2-1-5(11)12-9(13)16/h1-2,4,6-8,14-15H,3H2,(H2,11,12,16)/t4-,6?,7-,8-/m1/s1

Synonyms:

• 2'-Deoxy-2'-Chlorocytidine
• 2'-CHLORO-2'-DEOXYCYTIDINE
• -Chloro-2&rsquo
• Cytidine, 2'-chloro-2'-deoxy- (8CI,9CI)
• -deoxycytidine
• 2-CHLORO-2'-DEOXYCYTIDINE
• 4-Amino-1-((2R,3R,4R,5R)-3-chloro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one

2'-Chloro-2'-deoxycytidine

CAS: 10212-19-8

Formula: C₉H₁₂ClN₃O₄

Molecular weight: 261.6623

Ref: IN-DA0006OQ

2''-Chloro-2''-deoxycytidine

CAS: 10212-19-8

Formula: C₉H₁₂ClN₃O₄

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 261.70

Ref: 7W-GN7096

2'-Chloro-2'-deoxycytidine

CAS: 10212-19-8

Nucleoside Derivatives - Halo-nucleosides, 2’-Modified nucleosides

Formula: C₉H₁₂ClN₃O₄

Color and Shape: Solid

Molecular weight: 261.66

Ref: TM-TNU0074

2'-Chloro-2'-deoxycytidine

CAS: 10212-19-8

2'-Chloro-2'-deoxycytidine is a synthetic nucleoside analog. It is a modified deoxycytidine with a chlorine atom at the 2'-position of the deoxyribose sugar. This molecule can be used in research applications

Formula: C₉H₁₂ClN₃O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 261.66 g/mol

Ref: 3D-NC03763