CAS 10212-20-1

4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

Description:

4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one, with CAS number 10212-20-1, is a chemical compound characterized by its pyrimidine and sugar moiety structure. This compound features an amino group at the 4-position of the pyrimidine ring, which contributes to its potential biological activity. The presence of a fluorine atom and hydroxyl groups on the sugar moiety enhances its solubility and reactivity, making it of interest in medicinal chemistry, particularly in the development of antiviral or anticancer agents. The stereochemistry indicated by the (2R,3R,4R,5R) configuration suggests specific spatial arrangements that can influence the compound's interactions with biological targets. Additionally, the hydroxymethyl group may play a role in hydrogen bonding, further affecting its pharmacological properties. Overall, this compound exemplifies the complexity and diversity of chemical structures that can be explored for therapeutic applications.

Formula: C₉H₁₂FN₃O₄

InChI: InChI=1/C9H12FN3O4/c10-6-7(15)4(3-14)17-8(6)13-2-1-5(11)12-9(13)16/h1-2,4,6-8,14-15H,3H2,(H2,11,12,16)/t4-,6?,7-,8-/m1/s1

InChI key: InChIKey=NVZFZMCNALTPBY-XVFCMESISA-N

SMILES: F[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)N=C(N)C=C2

Synonyms:

• 2'-Deoxy-2'-Fluorocytidine
• 2'-Deoxy-2'-fluoro-D-cytidine
• 2'-Fc
• 2'-Fluoro-2'-Deoxycytidine
• 2'-Fluoro-D-Cytidine
• 2′-Fluoro-2′-deoxy-β-<span class="text-smallcaps">D</span>-ribofuranosylcytosine
• 4-Amino-1-((2R,3R,4R,5R)-3-Fluoro-4-Hydroxy-5-Hydroxymethyl-Tetrahydro-Furan-2-Yl)-1H-Pyrimidin-2-One
• 4-Amino-1-[3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
• 4-amino-1-(2-deoxy-2-fluoropentofuranosyl)pyrimidin-2(1H)-one
• Cytidine, 2′-deoxy-2′-fluoro-
• NSC 529432
• 2′-Fluoro-2′-deoxy-β-D-ribofuranosylcytosine
• 2'-DEOXY-2'-FLUOROCYTIDINE(2'-FLUORO-2'-DEOXYCYTIDINE, 2'-FC)
• 2'-Deoxy-2'-fluorocytidine Hydrate
• 2''-DEOXY-2''-FLUOROCYTIDINE,99+%
• RO-8013
• 2'-FdC
• 4-amino-1-[(2r,3r,4r,5r)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
• 1-(2-Fluoro-2-deoxy-β-D-arabinofuranosyl)cytosine

2'-Deoxy-2'-fluorocytidine

CAS: 10212-20-1

Formula: C₉H₁₂FN₃O₄

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 245.21

Ref: 3B-D3614

2'-Fluoro-2'-deoxycytidine, 99%

CAS: 10212-20-1

2'-Fluoro-2'-deoxycytidine is a potent inhibitor of the subgenomic hepatitis C virus replicon in Huh-7 cells. 2'-Fluoro-2'-deoxycytidine has been shown to inhibit Borna Disease virus replication and spread. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product

Formula: C₉H₁₂FN₃O₄

Purity: 99%

Molecular weight: 245.21

Ref: 02-J65632

Cytidine, 2'-deoxy-2'-fluoro-

CAS: 10212-20-1

Formula: C₉H₁₂FN₃O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 245.2077

Ref: IN-DA0006OP

2'-Deoxy-2'-fluorocytidine

CAS: 10212-20-1

2'-Deoxy-2'-fluorocytidine

Purity: ≥98%

Molecular weight: 245.21g/mol

Ref: 54-BUP17473

4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

CAS: 10212-20-1

4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

Purity: 98%

Molecular weight: 245.21g/mol

Ref: 54-PC105247

2''-Fluoro-2''-deoxycytidine

CAS: 10212-20-1

Formula: C₉H₁₂FN₃O₄

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 245.21

Ref: 7W-GE0680

2’-Deoxy-2’-fluoro Cytidine

CAS: 10212-20-1

Formula: C₉H₁₂FN₃O₄

Molecular weight: 245.21

Ref: 4Z-C-4512

2'-Deoxy-2'-fluorocytidine

CAS: 10212-20-1

2'-Deoxy-2'-fluorocytidine is an nucleoside analog and inhibits of Crimean-Congo hemorrhagic fever virus (CCHFV) replication potently.

Formula: C₉H₁₂FN₃O₄

Purity: 99.90%

Color and Shape: White Or Almost White Crystalline Powder

Molecular weight: 245.21

Ref: TM-T38238

2'-Deoxy-2'-fluorocytidine

CAS: 10212-20-1

2'-Deoxy-2'-fluorocytidine is a nucleoside analog with the potential as an Crimean-Congo hemorrhagic fever virus antiviral

Formula: C₉H₁₂FN₃O₄

Purity: Min. 98 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 245.21 g/mol

Ref: 3D-ND06189

2′-Deoxy-2′-fluorocytidine

CAS: 10212-20-1

Formula: C₉H₁₂FN₃O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 245.21

Ref: 10-F211882

2’-Deoxy-2’-fluoro Cytidine

Controlled Product

CAS: 10212-20-1

Applications 2'-Deoxy-2'-fluorocytidine is a potent inhibitor of the subgenomic hepatitis C virus replicon in Huh-7 cells. 2'-Deoxy-2'-fluorocytidine has been shown to inhibit Borna Disease virus replication and spread.
References Stuyver, L.J. et al.: Antimicrob. Agents Chemother., 48, 651 (2004); Bajramovic, J.J. et al.: Antiomicrob. Agents Chemother., 48, 1422 (2004);

Formula: C₉H₁₂FN₃O₄

Color and Shape: Neat

Molecular weight: 245.21

Ref: TR-D232945

2\'-Deoxy-2\'-fluoro Cytidine

CAS: 10212-20-1

Formula: C₉H₁₂FN₃O₄

Molecular weight: 245.21

Ref: ST-EA-CP-C151034