CAS 102129-66-8

L-Alanyl-N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-L-alaninamide

Description:

L-Alanyl-N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-L-alaninamide, with CAS number 102129-66-8, is a synthetic compound that belongs to the class of amino acid derivatives. This substance features a structure that includes two L-alanine moieties, which are amino acids characterized by their non-polar side chains. The compound also contains a chloro group and a ketone functional group, contributing to its reactivity and potential biological activity. Its molecular structure suggests it may interact with biological systems, possibly influencing protein synthesis or enzyme activity. The presence of the phenylmethyl group indicates potential lipophilicity, which could affect its solubility and permeability in biological membranes. Additionally, the compound's stereochemistry, particularly the (1S) configuration, may play a crucial role in its biological interactions and pharmacological properties. Overall, this compound's unique combination of functional groups and stereochemistry makes it of interest in medicinal chemistry and drug development.

Formula: C₁₆H₂₂ClN₃O₃

InChI: InChI=1S/C16H22ClN3O3/c1-10(18)15(22)19-11(2)16(23)20-13(14(21)9-17)8-12-6-4-3-5-7-12/h3-7,10-11,13H,8-9,18H2,1-2H3,(H,19,22)(H,20,23)/t10-,11-,13-/m0/s1

InChI key: InChIKey=ONICONPPGVXITG-GVXVVHGQSA-N

SMILES: [C@@H](CC1=CC=CC=C1)(NC([C@@H](NC([C@H](C)N)=O)C)=O)C(CCl)=O

Synonyms:

• AAF-CMK TRIFLUOROACETATE
• AAF-CMK TFA
• L-Alaninamide, L-alanyl-N-[3-chloro-2-oxo-1-(phenylmethyl)propyl]-, (S)-
• L-Alaninamide, L-alanyl-N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-
• L-Alanyl-N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-L-alaninamide
• (2S)-2-amino-N-[(2S)-2-{[(2S)-4-chloro-3-oxo-1-phenylbutan-2-yl]amino}propanoyl]propanamide (non-preferred name)
• H-ALA-ALA-PHE-CMK TFA
• H-AAF-CMK, TFA
• H-ALA-ALA-PHE-CHLOROMETHYLKETONE TFA
• ALA-ALA-PHE-CH2CL TRIFLUOROACETATE
• (L-ALANYL-L-ALANYL-L-PHENYLALANYL)CHLOROMETHANE TRIFLUOROACETATE

Ala-Ala-Phe-CH2Cl

CAS: 102129-66-8

Ala-Ala-Phe-CH2Cl is a research tool that can be used for the study of protein interactions, receptor pharmacology, and ion channels. It has been shown to inhibit the activity of potassium and calcium channels. This compound is also an activator for G protein coupled receptors, which are important mediators of cellular signaling. Ala-Ala-Phe-CH2Cl is an inhibitor of ion channels with high purity.

Formula: C₁₆H₂₂N₃O₃Cl

Purity: Min. 95%

Molecular weight: 339.82 g/mol

Ref: 3D-IAA-3202-V