CymitQuimica logo

CAS 102130-84-7

:

Nemadectin

Description:
Nemadectin is a macrocyclic lactone compound that belongs to the class of anthelmintics, primarily used for its efficacy against parasitic infections in various organisms, including nematodes and arthropods. It is derived from the fermentation of certain soil bacteria, specifically from the genus Streptomyces. The compound exhibits a broad spectrum of activity, making it valuable in agricultural and veterinary applications. Nemadectin functions by interfering with the neuromuscular transmission in parasites, leading to paralysis and eventual death. Its chemical structure features a large lactone ring, which is characteristic of many compounds in the avermectin family. The substance is typically administered in formulations that enhance its bioavailability and effectiveness. Safety profiles indicate that it has low toxicity to non-target organisms, making it a preferred choice in integrated pest management strategies. However, as with any chemical agent, proper handling and application guidelines should be followed to minimize environmental impact and resistance development in target populations.
Formula:C36H52O8
InChI:InChI=1/C36H52O8/c1-20(2)13-24(6)32-25(7)30(37)18-35(44-32)17-28-16-27(43-35)12-11-22(4)14-21(3)9-8-10-26-19-41-33-31(38)23(5)15-29(34(39)42-28)36(26,33)40/h8-11,13,15,20-21,25,27-33,37-38,40H,12,14,16-19H2,1-7H3/b9-8+,22-11+,24-13+,26-10+/t21-,25-,27+,28-,29-,30-,31+,32+,33+,35-,36+/m0/s1
Synonyms:
  • Nemadectin [USAN:INN]
  • (2aE,4E,4'S,5'S,6R,6'S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-6'-((E)-1,3-Dimethyl-1-butenyl)-3',4',5',6,6',7,10,11,14,15,17a,20,20a,20b-tetradecahydro-4',20,20b-trihydroxy-5',6,8,19-tetramethylspiro(11,15-methano-2H,13H,17H-furo(4,3,2-pq)(2,6)benzodioxacyclooctadecin-13,2'-(2H)pyran)-17-one
  • (6R,23S,25S)-5-O-Demethyl-28-deoxy-25-((E)-1,3-dimethyl-1-butenyl)-6,28-epoxy-23-hydroxymilbemycin B
  • Cl 287,088
  • F28249alpha
  • Milbemycin B, 5-O-demethyl-28-deoxy-25-(1,3-dimethyl-1-butenyl)-6,28-epoxy-23-hydroxy-, (6R,23S,25S(E))-
  • Nemadectina
  • Nemadectina [INN-Spanish]
  • Nemadectine
  • Nemadectine [INN-French]
  • See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 4 products.