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CAS 102185-38-6

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N(alpha)-boc-N(omega)-mtr-L-arginine

Description:
N(alpha)-Boc-N(omega)-mtr-L-arginine, commonly referred to as a protected form of the amino acid L-arginine, is characterized by the presence of a tert-butyloxycarbonyl (Boc) group at the alpha position and a 4-methyltrityl (mtr) group at the omega position of the arginine side chain. This compound is typically used in peptide synthesis as a means to protect the amino and guanidinium functionalities of arginine, allowing for selective reactions without interference from these reactive sites. The Boc group is a common protecting group that can be easily removed under mild acidic conditions, while the mtr group provides stability against nucleophilic attack and can be removed under specific conditions, often involving strong acids. The presence of these protective groups enhances the compound's solubility in organic solvents and contributes to its stability during synthesis. N(alpha)-Boc-N(omega)-mtr-L-arginine is utilized in various biochemical applications, including the synthesis of peptides and the study of protein interactions, due to its ability to mimic the natural amino acid while providing necessary functional group protection.
Formula:C20H32N4O6S
InChI:InChI=1/C20H32N4O6S/c1-12-10-13(2)16(14(3)11-12)31(28,29)24-18(21)22-9-7-8-15(17(25)26)23-19(27)30-20(4,5)6/h10-11,15H,7-9H2,1-6H3,(H,23,27)(H,25,26)(H3,21,22,24)/t15-/m0/s1
SMILES:Cc1cc(C)c(c(C)c1)S(=O)(=O)NC(=N)NCCC[C@@H](C(=O)O)N=C(O)OC(C)(C)C
Synonyms:
  • na-T-boc-N-omega-(4-methoxy-2,3,6-*trimethylbenze
  • Boc-Arg(Mtr)-OH
  • Boc-Arg(Mts)-OH
  • (2S)-2-(tert-butoxycarbonylamino)-5-[[N-(2,4,6-trimethylphenyl)sulfonylcarbamimidoyl]amino]pentanoic acid
  • N-alpha-BOC-N(G)-Mesitylenesulfonyl-L-Arginine
  • N-alpha-T-butoxycarbonyl-N-OMEGA-(2-Mesitylenesulfonyl)-L-Arginine 2-Mesitylenesulfonyl
  • N-alpha-TERT-BUTYLOXYCARBONYL-N'-(Mesitylene-2-sulfonyl)-L-Arginine
  • N-alpha-T-BOC-N-OMEGA-Mesitylene-sulfonyl-L-Arginine MONOCYCLOHEXYLAMMONIUM SALT
  • BOC-N-OMEGA-(Mesitylene-2-sulfonyl)-L-Arginine
  • BOC-L-Arginine (MTS)
  • See more synonyms
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