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CAS 1021860-94-5

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4-Methyl-2-trifluoromethyl-phenylboronic acid

Description:
4-Methyl-2-trifluoromethyl-phenylboronic acid is an organoboron compound characterized by the presence of a boronic acid functional group, which is known for its ability to form reversible covalent bonds with diols, making it useful in various applications, including organic synthesis and medicinal chemistry. This compound features a phenyl ring substituted with a methyl group and a trifluoromethyl group, which can influence its electronic properties and reactivity. The trifluoromethyl group is particularly notable for its electron-withdrawing effects, which can enhance the acidity of the boronic acid moiety. The compound is typically a solid at room temperature and may exhibit moderate solubility in polar solvents. Its reactivity allows it to participate in cross-coupling reactions, such as Suzuki-Miyaura coupling, which is widely used in the formation of carbon-carbon bonds. Additionally, the presence of fluorine atoms can impart unique characteristics, such as increased lipophilicity and altered biological activity, making it a compound of interest in pharmaceutical research.
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