CAS 1021933-98-1

O-DESMETHYL-(RAC-VENLAFAXINE) GLUCURONIDE

Description:

O-Desmethyl-(Rac)-venlafaxine glucuronide is a metabolite of venlafaxine, an antidepressant commonly used to treat major depressive disorder and anxiety disorders. This compound is characterized by its glucuronide conjugate structure, which results from the phase II metabolism of venlafaxine, involving the addition of a glucuronic acid moiety. The presence of the glucuronide group typically enhances the solubility and excretion of the parent drug. O-Desmethyl-(Rac)-venlafaxine itself is an active metabolite, contributing to the pharmacological effects of venlafaxine. The compound is generally studied in the context of pharmacokinetics and drug metabolism, particularly in understanding how venlafaxine is processed in the body and its potential effects on therapeutic outcomes. Its chemical properties, such as solubility, stability, and interaction with biological systems, are crucial for assessing its role in drug efficacy and safety. As with many metabolites, the specific characteristics can vary based on the biological environment and the presence of other substances.

Formula: C₂₂H₃₃NO₈

Synonyms:

• 4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenyl-D-Glucopyranosiduronic Acid
• rac O-Desmethyl Venlafaxine -D-Glucuronide
• 4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenyl beta-D-glucopyranosiduronic acid
• O-DESMETHYL-(RAC-VENLAFAXINE) GLUCURONIDE

rac O-Desmethyl Venlafaxine b-D-Glucuronide

CAS: 1021933-98-1

Formula: C₂₂H₃₃NO₈

Color and Shape: Solid

Molecular weight: 439.4993

Ref: IN-DA0006V3

rac O-desmethyl venlafaxine b-D-glucuronide

CAS: 1021933-98-1

Ref: 7W-GC1802

O-Desmethyl Venlafaxine Glucuronide Lithium Salt (Mixture of Diastereomers)

CAS: 1021933-98-1

Formula: C₂₂H₃₂NO₈·Li

Color and Shape: White To Off-White Solid

Molecular weight: 438.50 6.94

Ref: 4Z-V-037

rac O-Desmethyl Venlafaxine β-D-Glucuronide

Controlled Product

CAS: 1021933-98-1

Applications A metabolite of Venlafaxine, a selective serotonin noradrenaline reuptake inhibitor. Used as an antidepressant.
References Kelsey, J., et al.: J. Clin. Psychopharmacol., 16, 21 (1996), Long, C., et al.: J. Anal. Toxicol., 21, 166 (1997), Deecher, D., et al.: J. Pharmacol. Exp. Ther., 318, 657 (2006)

Formula: C₂₂H₃₃NO₈

Color and Shape: Neat

Molecular weight: 439.50

Ref: TR-D296525

rac O-Desmethyl venlafaxine b-D-glucuronide

Controlled Product

CAS: 1021933-98-1

Rac O-Desmethyl venlafaxine b-D-glucuronide is a synthetic glycosylated monosaccharide with a custom synthesis. It is fluorinated with the use of fluorination in order to increase its potency and stability. Rac O-Desmethyl venlafaxine b-D-glucuronide has been modified to have a click modification and has been shown to be stable against degradation by enzymes, such as monoamine oxidase B. This product is high purity and can be used in pharmaceuticals or research.

Formula: C₂₂H₃₃NO₈

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 439.5 g/mol

Ref: 3D-MD16846