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CAS 102195-79-9

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Boc-cis-Hyp-OMe

Description:
Boc-cis-Hyp-OMe, also known as Boc-cis-4-hydroxyproline methyl ester, is a derivative of the amino acid hydroxyproline, characterized by the presence of a tert-butyloxycarbonyl (Boc) protecting group and a methyl ester functionality. This compound is typically used in peptide synthesis and medicinal chemistry due to its ability to stabilize peptide bonds and influence the conformation of peptides. The cis configuration of the hydroxyproline moiety is significant, as it can affect the biological activity and structural properties of the resulting peptides. The Boc group serves as a protective group that can be removed under acidic conditions, allowing for further functionalization or coupling reactions. The methyl ester enhances solubility and can facilitate the incorporation of the amino acid into larger peptide chains. Overall, Boc-cis-Hyp-OMe is a valuable building block in the synthesis of bioactive peptides and pharmaceuticals, contributing to the development of compounds with specific therapeutic properties.
Formula:C11H19NO5
InChI:InChI=1/C11H19NO5/c1-11(2,3)17-10(15)12-6-7(13)5-8(12)9(14)16-4/h7-8,13H,5-6H2,1-4H3/t7-,8-/m0/s1
SMILES:CC(C)(C)OC(=O)N1C[C@H](C[C@H]1C(=O)OC)O
Synonyms:
  • N-Boc-cis-4-Hydroxy-L-proline methyl ester
  • 1-Tert-Butyl 2-Methyl 4-Hydroxypyrrolidine-1,2-Dicarboxylate
  • 1-tert-butyl 2-methyl (2S,4S)-4-hydroxypyrrolidine-1,2-dicarboxylate
  • N-T-Boc-Cis-4-Hydroxyl-L-Proline Methyl Ester
  • 1-Tert-Butyl 2-Methyl Cis-4-Hydroxypyrrolidine-1,2-Dicarboxylate
  • cis-Boc-Hyp-Ome
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