CAS 1022-31-7

N-Formylkynurenine

Description:

N-Formylkynurenine is an intermediate compound in the kynurenine pathway, which is a significant metabolic route for the amino acid tryptophan. This substance is characterized by its structure, which includes a formyl group attached to the kynurenine backbone. It is known to exhibit biological activity, particularly in the context of neurobiology and immunology, as it can influence various physiological processes, including the modulation of immune responses and neuroprotective effects. N-Formylkynurenine is soluble in polar solvents, which facilitates its interactions in biological systems. Its role in the production of other metabolites, such as kynurenic acid and quinolinic acid, highlights its importance in the synthesis of neuroactive compounds. Additionally, research has indicated that N-formylkynurenine may have implications in the pathophysiology of certain diseases, including neurodegenerative disorders. Overall, this compound serves as a crucial link in the complex interplay of tryptophan metabolism and its associated biological functions.

Formula: C₁₁H₁₂N₂O₄

InChI: InChI=1S/C11H12N2O4/c12-8(11(16)17)5-10(15)7-3-1-2-4-9(7)13-6-14/h1-4,6,8H,5,12H2,(H,13,14)(H,16,17)

InChI key: InChIKey=BYHJHXPTQMMKCA-UHFFFAOYSA-N

SMILES: C(CC(C(O)=O)N)(=O)C1=C(NC=O)C=CC=C1

Synonyms:

• (2S)-2-amino-4-[2-(formylamino)phenyl]-4-oxobutanoic acid
• 2-Amino-4-(2-formamidophenyl)-4-oxobutanoic acid
• 2-Amino-4-[2-(Formylamino)Phenyl]-4-Oxobutanoic Acid
• Alanine, 3-(N-formylanthraniloyl)-
• Benzenebutanoic acid, α-amino-2-(formylamino)-γ-oxo-
• Formylkynurenine
• Kynurenine, N′-formyl-
• N'-Formylkynurenine
• α-Amino-2-(formylamino)-γ-oxobenzenebutanoic acid

Benzenebutanoic acid, α-amino-2-(formylamino)-γ-oxo-

CAS: 1022-31-7

Formula: C₁₁H₁₂N₂O₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 236.2240

Ref: IN-DA0006W6

2-Amino-4-(2-formamidophenyl)-4-oxobutanoic acid

CAS: 1022-31-7

2-Amino-4-(2-formamidophenyl)-4-oxobutanoic acid

Purity: 97%

Molecular weight: 236.23g/mol

Ref: 54-OR1054430

N-Formyl Kynurenine

CAS: 1022-31-7

Formula: C₁₁H₁₂N₂O₄

Molecular weight: 236.23

Ref: 4Z-K-008007

N'-Formylkynurenine

CAS: 1022-31-7

Stability Hygroscopic
Applications N'-Formylkynurenine is a photooxidation product of Tryptophan (T947200), and is also used as a photosensitizer of near-ultraviolet radiation by generating singlet oxygen and superoxide.
References Grossweiner, L.: Curr. Eye Res., 3, 137 (1984); Møller, I. & Kristensen, B.: Free Radical Bio. Med., 40, 430 (2006); Pileni, M., et al.: J. Phys. Chem., 80, 1804 (1976)

Formula: C₁₁H₁₂N₂O₄

Color and Shape: Off White To Dark Beige

Molecular weight: 236.22

Ref: TR-F700490