CAS 1022094-34-3

5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-[[[[4-[[L-valyl-N5-(aminocarbonyl)-L-ornithyl]amino]phenyl]methoxy]carbonyl]amino]-α-L-lyxo-hexopyranosyl]oxy]-, (8S,10S)-

Description:

5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-[[[[4-[[L-valyl-N5-(aminocarbonyl)-L-ornithyl]amino]phenyl]methoxy]carbonyl]amino]-α-L-lyxo-hexopyranosyl]oxy]-, (8S,10S)- is a complex organic compound characterized by its intricate structure, which includes multiple functional groups such as hydroxyl (-OH), methoxy (-OCH3), and amine (-NH2) groups. This compound features a naphthacene backbone, which contributes to its potential biological activity and stability. The presence of various substituents, including a trideoxy sugar moiety and amino acid derivatives, suggests that it may exhibit significant interactions in biological systems, possibly influencing its solubility and reactivity. The stereochemistry indicated by the (8S,10S) configuration implies specific spatial arrangements that can affect the compound's pharmacological properties. Overall, this substance may have applications in medicinal chemistry, particularly in the development of therapeutic agents, due to its structural complexity and potential bioactivity.

Formula: C₄₆H₅₆N₆O₁₆

Synonyms:

• 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-[[[[4-[[L-valyl-N5-(aminocarbonyl)-L-ornithyl]amino]phenyl]methoxy]carbonyl]amino]-α-L-lyxo-hexopyranosyl]oxy]-, (8S,10S)-

Val-Cit-PABC-DOX

CAS: 1022094-34-3

Val-Cit-PABC-DOX (compound 10109), a conjugate based on epsilon-poly-L-lysine, functions as an agent-linker for ADC, employing Doxorubicin—an inhibitor of both DNA topoisomerase I and II—as the linked agent via the Val-Cit-PABC linker.

Formula: C₄₆H₅₆N₆O₁₆

Color and Shape: Solid

Molecular weight: 948.97

Ref: TM-T88212

Val-Cit-PABC-DOX

CAS: 1022094-34-3

Formula: C₄₆H₅₆N₆O₁₆

Molecular weight: 948.98

Ref: ST-EA-CP-D102041