CAS 1022150-57-7

6-((6-(1-methyl-1h-pyrazol-4-yl)-1,2,4-triazolo(4,3-b)pyridazin-3-yl)thio)quinoline

Description:

The chemical substance known as "6-((6-(1-methyl-1H-pyrazol-4-yl)-1,2,4-triazolo(4,3-b)pyridazin-3-yl)thio)quinoline" is a complex organic compound characterized by its multi-ring structure, which includes a quinoline moiety and various heterocycles such as pyrazole and triazole. This compound features a thioether linkage, indicating the presence of a sulfur atom bonded to carbon, which can influence its reactivity and solubility. The presence of multiple nitrogen atoms within the heterocyclic rings contributes to its potential biological activity, making it of interest in medicinal chemistry. Such compounds often exhibit diverse pharmacological properties, including antimicrobial, anti-inflammatory, or anticancer activities. The specific arrangement of functional groups and the overall molecular architecture can significantly affect the compound's interactions with biological targets. Additionally, the CAS number 1022150-57-7 serves as a unique identifier for this substance, facilitating its identification in chemical databases and literature. Overall, this compound represents a class of molecules that may have significant implications in drug discovery and development.

Formula: C₁₈H₁₃N₇S

InChI: InChI=1S/C18H13N7S/c1-24-11-13(10-20-24)16-6-7-17-21-22-18(25(17)23-16)26-14-4-5-15-12(9-14)3-2-8-19-15/h2-11H,1H3

InChI key: InChIKey=BCZUAADEACICHN-UHFFFAOYSA-N

SMILES: S(C=1N2C(=NN1)C=CC(=N2)C=3C=NN(C)C3)C4=CC5=C(C=C4)N=CC=C5

Synonyms:

• Quinoline, 6-[[6-(1-methyl-1H-pyrazol-4-yl)-1,2,4-triazolo[4,3-b]pyridazin-3-yl]thio]-
• Sgx-523
• 6-[[6-(1-Methyl-1H-pyrazol-4-yl)-1,2,4-triazolo[4,3-b]pyridazin-3-yl]thio]quinoline

SGX-523

CAS: 1022150-57-7

Formula: C₁₈H₁₃N₇S

Purity: 99%

Color and Shape: Solid

Molecular weight: 359.4077

Ref: IN-DA008TJH

SGX-523

CAS: 1022150-57-7

SGX-523

Purity: ≥98%

Molecular weight: 359.41g/mol

Ref: 54-BUP03937

SGX-523

CAS: 1022150-57-7

SGX-523 is a selective Met inhibitor (IC50: 4 nM), no inhibitory to Abl, BRAFV599E, p38α, and c-Raf.

Formula: C₁₈H₁₃N₇S

Purity: 99% - >99.99%

Color and Shape: Solid

Molecular weight: 359.41

Ref: TM-T2293

SGX-523

CAS: 1022150-57-7

Ref: 7W-GW4900

SGX 523

CAS: 1022150-57-7

Inhibits c-MET tyrosine kinases

Formula: C₁₈H₁₃N₇S

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 359.09531

Ref: 3D-FM32803