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CAS 1022922-16-2

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(2-Chloro-5-(trifluoromethoxy)phenyl)boronicacid

Description:
(2-Chloro-5-(trifluoromethoxy)phenyl)boronic acid is an organoboron compound characterized by the presence of a boronic acid functional group, which is known for its ability to form reversible covalent bonds with diols, making it useful in various applications, including organic synthesis and medicinal chemistry. The compound features a chloro substituent and a trifluoromethoxy group on a phenyl ring, which can influence its reactivity and solubility. The trifluoromethoxy group is particularly notable for its electron-withdrawing properties, which can enhance the acidity of the boronic acid moiety. This compound is typically used in cross-coupling reactions, such as Suzuki-Miyaura coupling, to form carbon-carbon bonds. Its unique structural features may also impart specific biological activities, making it a candidate for further investigation in pharmaceutical research. Additionally, the presence of fluorine atoms can enhance the compound's stability and lipophilicity, which are important factors in drug design and development. Overall, (2-Chloro-5-(trifluoromethoxy)phenyl)boronic acid is a versatile compound with significant implications in both synthetic and medicinal chemistry.
Formula:C7H5BClF3O3
Synonyms:
  • 2-Chloro-5-(Trifluoromethoxy)Phenylboronic Acid
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